methyl (E)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate

Base Information

Chemical Name:methyl (E)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate
CAS No.:1026950-63-9
Molecular Formula:C₂₆H₃₂O₉S
Molecular Weight:520.601
Hs Code.:

Synonyms:methyl (E)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate

Suppliers and Price of methyl (E)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (E)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (E)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate

There total 3 articles about methyl (E)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 102736-25-4
3-(phenylthio)-1-(trimethylsiloxy)-1-methoxy-1,3-butadiene

: 159124-49-9
triethyl 4-oxo-2-cyclohexene-1,1,3-tricarboxylate

: 1026950-63-9
methyl (E)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate

: methyl (Z)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate

Guidance literature:: With titanium tetrachloride; In dichloromethane; at -78 ℃; for 1.08333h; Yield given. Yields of byproduct given;
DOI:10.1021/jo00101a033

Reference yield:

: 57899-62-4
triethyl 4-oxocyclohexane-1,1,3-tricarboxylate

: 1026950-63-9
methyl (E)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) pyridine / 1.) CH₂Cl₂, 0 deg C, 15 min, 2.) 0 deg C, 1 h; 0 - 10 deg C, 30 min

2: 84 percent / 30percent aq. H₂O₂ / CH₂Cl₂ / 0.5 h / 0 °C

3: TiCl₄ / CH₂Cl₂ / 1.08 h / -78 °C

With pyridine; dihydrogen peroxide; titanium tetrachloride; In dichloromethane;
DOI:10.1021/jo00101a033

Reference yield:

: 159124-47-7
triethyl 4-oxo-3-(phenylseleno)cyclohexane-1,1,3-tricarboxylate

: 1026950-63-9
methyl (E)-3-(phenylthio)-4-(2',2',6'-tris(ethoxycarbonyl)-5'-oxocyclohexyl)but-2-enoate

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / 30percent aq. H₂O₂ / CH₂Cl₂ / 0.5 h / 0 °C

2: TiCl₄ / CH₂Cl₂ / 1.08 h / -78 °C

With dihydrogen peroxide; titanium tetrachloride; In dichloromethane;
DOI:10.1021/jo00101a033