9-mercaptodethiobiotin

Base Information

Chemical Name:9-mercaptodethiobiotin
CAS No.:139936-57-5
Molecular Formula:C₁₀H₁₈N₂O₃S
Molecular Weight:246.331
Hs Code.:
Mol file:139936-57-5.mol

Synonyms:4-Imidazolidinehexanoicacid, 5-(mercaptomethyl)-2-oxo-, cis- (9CI); 4-Imidazolidinehexanoic acid,5-(mercaptomethyl)-2-oxo-, cis-(?à)-

Suppliers and Price of 9-mercaptodethiobiotin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 9-mercaptodethiobiotin

Chemical Property:

Vapor Pressure:3.15E-13mmHg at 25°C
Boiling Point:543°Cat760mmHg
Flash Point:282.2°C
PSA：120.72000
Density:1.169g/cm³
LogP:0.97010

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 9-mercaptodethiobiotin

There total 13 articles about 9-mercaptodethiobiotin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 6-((4S,5S)-1-Acetyl-5-mercaptomethyl-2-oxo-imidazolidin-4-yl)-hexanoic acid ethyl ester

: 139936-57-5
(+/-)-9-mercaptodethiobiotin

Guidance literature:: With sodium hydroxide; In methanol; at 40 ℃; for 4h;
DOI:10.1021/ja00059a006

Reference yield:

: 6-((4S,5S)-1-Acetyl-5-hydroxymethyl-2-oxo-imidazolidin-4-yl)-hexanoic acid ethyl ester

: 139936-57-5
(+/-)-9-mercaptodethiobiotin

Guidance literature:: Multi-step reaction with 4 steps

1: 58 percent / Et₃N / CH₂Cl₂ / 0.5 h / -10 °C

2: 64 percent / dimethylformamide / 48 h / 100 °C

3: 17 mg / NaBH₄ / ethanol / 8 h / Ambient temperature

4: 72 percent / 4 N NaOH / methanol / 4 h / 40 °C

With sodium hydroxide; sodium tetrahydroborate; triethylamine; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja00059a006

Reference yield:

: 6-((4S,5S)-1-Acetyl-2-oxo-5-thiocyanatomethyl-imidazolidin-4-yl)-hexanoic acid ethyl ester

: 139936-57-5
(+/-)-9-mercaptodethiobiotin

Guidance literature:: Multi-step reaction with 2 steps

1: 17 mg / NaBH₄ / ethanol / 8 h / Ambient temperature

2: 72 percent / 4 N NaOH / methanol / 4 h / 40 °C

With sodium hydroxide; sodium tetrahydroborate; In methanol; ethanol;
DOI:10.1021/ja00059a006