2-chloro-N-[2-(trifluoromethyl)phenyl]benzamide

Base Information

• Chemical Name: 2-chloro-N-[2-(trifluoromethyl)phenyl]benzamide
• CAS No.: 3873-78-7
• Molecular Formula: C₁₄H₉ClF₃NO
• Molecular Weight: 299.68
• Hs Code.: 2924299090
• NSC Number: 142156
• DSSTox Substance ID: DTXSID40959543
• Mol file: 3873-78-7.mol

Synonyms:2-chloro-N-[2-(trifluoromethyl)phenyl]benzamide;3873-78-7;2-Chloro-N-(2-(trifluoromethyl)phenyl)benzamide;NSC142156;ChemDiv3_000716;DTXSID40959543;HMS1475A12;STK069046;AKOS001604076;NSC-142156;IDI1_019682;NCGC00328629-01;AB00081671-01;AB00081671-03;AK-968/11164551;SR-01000406886;SR-01000406886-1;2-Chloro-N-[2-(trifluoromethyl)phenyl]benzene-1-carboximidic acid

Chemical Property of 2-chloro-N-[2-(trifluoromethyl)phenyl]benzamide

Chemical Property:

• Vapor Pressure: 0.00125mmHg at 25°C
• Boiling Point: 298.7°Cat760mmHg
• Flash Point: 134.4°C
• PSA: 29.10000
• Density: 1.401g/cm³
• LogP: 4.68410
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 299.0324761
• Heavy Atom Count: 20
• Complexity: 348

Purity/Quality:

99% ^*data from raw suppliers

2-CHLORO-N-(2-(TRIFLUOROMETHYL)PHENYL)BENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(=O)NC2=CC=CC=C2C(F)(F)F)Cl

Technology Process of 2-chloro-N-[2-(trifluoromethyl)phenyl]benzamide

There total 2 articles about 2-chloro-N-[2-(trifluoromethyl)phenyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

2-chlorobenzanilide (6833-13-2) + Langlois reagent (2926-29-6) → 2-chloro-N-(2-(trifluoromethyl)phenyl)benzamide (3873-78-7)

Guidance literature:

With ammonium peroxydisulfate; eosin y; copper dichloride; In acetonitrile; for 20h; Sealed tube; Irradiation;

DOI:10.1021/acs.joc.9b01987

Reference yield:

→ 2-chloro-N-(2-(trifluoromethyl)phenyl)benzamide (3873-78-7)

Guidance literature:

/BRN= 3319864/;

upstream raw materials:

2-chlorobenzanilide

Langlois reagent