1-benzyloxycarbonyl-6-chloro-3-(R)-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline

Base Information

Chemical Name:1-benzyloxycarbonyl-6-chloro-3-(R)-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline
CAS No.:333954-39-5
Molecular Formula:C₁₈H₁₈ClNO₃
Molecular Weight:331.799
Hs Code.:

Synonyms:1-benzyloxycarbonyl-6-chloro-3-(R)-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline

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Chemical Property of 1-benzyloxycarbonyl-6-chloro-3-(R)-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline

Chemical Property:

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Technology Process of 1-benzyloxycarbonyl-6-chloro-3-(R)-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline

There total 6 articles about 1-benzyloxycarbonyl-6-chloro-3-(R)-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 333954-40-8
1-benzyloxycarbonyl-6-chloro-3-(R)-hexanoyloxymethyl-1,2,3,4-tetrahydroquinoline

: 333954-39-5
1-benzyloxycarbonyl-6-chloro-3-(R)-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; water;

Reference yield:

: 333954-33-9
2-(5-chloro-2-nitrobenzyl)propane-1,3-diol

: 333954-39-5
1-benzyloxycarbonyl-6-chloro-3-(R)-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 6 steps

1: lipase

2: sodium bicarbonate; triethylamine / acetonitrile

3: acetic acid / tetrahydrofuran

4: N-ethyl-N,N-diisopropylamine / tetrahydrofuran

5: sodium bicarbonate / pyridine; water

6: sodium hydroxide / tetrahydrofuran; methanol; water

With sodium hydroxide; sodium bicarbonate; acetic acid; triethylamine; N-ethyl-N,N-diisopropylamine; lipase; In tetrahydrofuran; pyridine; methanol; water; acetonitrile;

Reference yield:

: 333954-38-4
2-(S)-(2-amino-5-chlorobenzyl)-3-[(methylsulfonyl)oxy]propyl hexanoate

: 333954-39-5
1-benzyloxycarbonyl-6-chloro-3-(R)-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran

2: sodium bicarbonate / pyridine; water

3: sodium hydroxide / tetrahydrofuran; methanol; water

With sodium hydroxide; sodium bicarbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; pyridine; methanol; water;