(1R,2R)-tert-butyl 2-(5-(benzyloxy)pentanoyl)cyclopropane carboxylate

Base Information

• Chemical Name: (1R,2R)-tert-butyl 2-(5-(benzyloxy)pentanoyl)cyclopropane carboxylate
• CAS No.: 1035930-64-3
• Molecular Formula: C₂₀H₂₈O₄
• Molecular Weight: 332.44
• Mol file: 1035930-64-3.mol

Synonyms:(1R,2R)-tert-butyl 2-(5-(benzyloxy)pentanoyl)cyclopropane carboxylate

Chemical Property of (1R,2R)-tert-butyl 2-(5-(benzyloxy)pentanoyl)cyclopropane carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (1R,2R)-tert-butyl 2-(5-(benzyloxy)pentanoyl)cyclopropane carboxylate

There total 1 articles about (1R,2R)-tert-butyl 2-(5-(benzyloxy)pentanoyl)cyclopropane carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

7-(benzyloxy)hept-1-en-3-one (1035930-62-1) + bromoacetic acid tert-butyl ester (5292-43-3) → (1R,2R)-tert-butyl 2-(5-(benzyloxy)pentanoyl)cyclopropane carboxylate (1035930-64-3)

Guidance literature:

With caesium carbonate; In acetonitrile; at 80 ℃; for 20h;

DOI:10.1021/jo800631z

Reference yield: 69.0%

(1R,2R)-tert-butyl 2-(5-(benzyloxy)pentanoyl)cyclopropane carboxylate (1035930-64-3) → (1R,2R)-tert-butyl 2-((R)-5-(benzyloxy)-1-hydroxypentyl)cyclopropanecarboxylate (1035930-87-0) + (1R,2R)-tert-butyl 2-((S)-5-(benzyloxy)-1-hydroxypentyl)cyclopropanecarboxylate (1035930-68-7)

Guidance literature:

With potassium hydroxide; (R,R)-1,2-diphenylethylenediamine-based ruthenium complex; In dichloromethane; isopropyl alcohol; at 80 ℃; for 6h;

DOI:10.1021/jo800631z

upstream raw materials:

7-(benzyloxy)hept-1-en-3-one

bromoacetic acid tert-butyl ester

Downstream raw materials:

(1R,2R)-tert-butyl 2-((R)-5-(benzyloxy)-1-hydroxypentyl)cyclopropanecarboxylate

(1R,2R)-tert-butyl 2-((S)-5-(benzyloxy)-1-hydroxypentyl)cyclopropanecarboxylate