rac-(2S,3S)-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran

Base Information

Chemical Name:rac-(2S,3S)-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran
CAS No.:104761-78-6
Molecular Formula:C₁₇H₁₈O₄
Molecular Weight:286.328
Hs Code.:

Synonyms:rac-(2S,3S)-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran

Suppliers and Price of rac-(2S,3S)-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of rac-(2S,3S)-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of rac-(2S,3S)-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran

There total 6 articles about rac-(2S,3S)-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 104761-77-5
rac-(2S,3S)-6-(benzyloxy)-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran

: 104761-78-6
rac-(2S,3S)-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; for 4h; Ambient temperature;
DOI:10.1021/jm00384a023

Reference yield:

: 18523-76-7
(E)-3',4'-dimethoxycinnamyl alcohol

: 104761-78-6
rac-(2S,3S)-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran

Guidance literature:: Multi-step reaction with 3 steps

1: 24 percent / diethyl azodicarboxylate, triphenylphosphine / tetrahydrofuran / 1 h / Ambient temperature

2: 43 percent / diethylaniline / 2 h / 220 °C

3: 74 percent / H₂ / 10percent Pd on C / ethyl acetate; methanol / 4 h / Ambient temperature

With hydrogen; triphenylphosphine; N,N-diethylaniline; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; methanol; ethyl acetate;
DOI:10.1021/jm00384a023

Reference yield:

: 14737-89-4
3,4-dimethoxy-trans-cinnamic acid

: 104761-78-6
rac-(2S,3S)-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran

Guidance literature:: Multi-step reaction with 4 steps

1: 62 percent / LiAlH₄ / tetrahydrofuran / 2 h / Ambient temperature

2: 24 percent / diethyl azodicarboxylate, triphenylphosphine / tetrahydrofuran / 1 h / Ambient temperature

3: 43 percent / diethylaniline / 2 h / 220 °C

4: 74 percent / H₂ / 10percent Pd on C / ethyl acetate; methanol / 4 h / Ambient temperature

With lithium aluminium tetrahydride; hydrogen; triphenylphosphine; N,N-diethylaniline; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; methanol; ethyl acetate;
DOI:10.1021/jm00384a023