5,10-di(tert-butoxycarbonyl)-15-(4-methoxybenzyloxycarbonyl)-5,10,15-triazapentadecylamine

Base Information

• Chemical Name: 5,10-di(tert-butoxycarbonyl)-15-(4-methoxybenzyloxycarbonyl)-5,10,15-triazapentadecylamine
• CAS No.: 1247878-75-6
• Molecular Formula: C₃₁H₅₄N₄O₇
• Molecular Weight: 594.792
• Mol file: 1247878-75-6.mol

Synonyms:5,10-di(tert-butoxycarbonyl)-15-(4-methoxybenzyloxycarbonyl)-5,10,15-triazapentadecylamine

Chemical Property of 5,10-di(tert-butoxycarbonyl)-15-(4-methoxybenzyloxycarbonyl)-5,10,15-triazapentadecylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 5,10-di(tert-butoxycarbonyl)-15-(4-methoxybenzyloxycarbonyl)-5,10,15-triazapentadecylamine

There total 1 articles about 5,10-di(tert-butoxycarbonyl)-15-(4-methoxybenzyloxycarbonyl)-5,10,15-triazapentadecylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1-azido-5,10-di(tert-butoxycarbonyl)-15-(4-methoxybenzyloxycarbonyl)-5,10,15-triazapentadecane (1247878-74-5) → 5,10-di(tert-butoxycarbonyl)-15-(4-methoxybenzyloxycarbonyl)-5,10,15-triazapentadecylamine (1247878-75-6)

Guidance literature:

With 3.5-6.5% Pd/C; hydrogen; ethylenediamine; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1248/cpb.58.862

Reference yield: 66.0%

5,10-di(tert-butoxycarbonyl)-15-(4-methoxybenzyloxycarbonyl)-5,10,15-triazapentadecylamine (1247878-75-6) + N,N'-bis-Boc-S-methyl-isothiourea (322474-21-5) → N-(4-{[4-(4-methoxybenzyloxycarbonylamino)butyl]-(tert-butoxycarbonyl)amino}butyl)-N-{4-[N',N''-bis(tert-butoxycarbonyl)guanidino]butyl}carbamic acid tert-butyl ester (1247878-76-7)

Guidance literature:

In dichloromethane; at 20 ℃; for 48h;

DOI:10.1248/cpb.58.862

upstream raw materials:

1-azido-5,10-di(tert-butoxycarbonyl)-15-(4-methoxybenzyloxycarbonyl)-5,10,15-triazapentadecane

Downstream raw materials:

N-(4-{[4-(4-methoxybenzyloxycarbonylamino)butyl]-(tert-butoxycarbonyl)amino}butyl)-N-{4-[N',N''-bis(tert-butoxycarbonyl)guanidino]butyl}carbamic acid tert-butyl ester