4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzenecarbohydrazide

Base Information

• Chemical Name: 4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzenecarbohydrazide
• CAS No.: 351010-97-4
• Molecular Formula: C₂₀H₂₁N₃O₃
• Molecular Weight: 351.405
• Mol file: 351010-97-4.mol

Synonyms:4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzenecarbohydrazide

Chemical Property of 4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzenecarbohydrazide

Chemical Property:

Purity/Quality:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzenecarbohydrazide

There total 1 articles about 4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzenecarbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzoyl chloride → 4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzenecarbohydrazide (351010-97-4)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; at 20 ℃; for 1.5h;

DOI:10.1002/jhet.5570380202

Reference yield: 67.0%

4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzenecarbohydrazide (351010-97-4) → 4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzeneisocyanate (351010-99-6)

Guidance literature:

4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzenecarbohydrazide; With acetic acid; sodium nitrite; at 0 ℃; for 0.5h;

In toluene; at 90 ℃; for 2h;

DOI:10.1002/jhet.5570380202

Reference yield:

4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzenecarbohydrazide (351010-97-4) → [4-(7-diethylamino-2-oxo-2H-chromen-3-yl)-phenyl]-carbamic acid hexadecyl ester

Guidance literature:

Multi-step reaction with 2 steps

1.1: aq. NaNO₂; AcOH / 0.5 h / 0 °C

1.2: 67 percent / toluene / 2 h / 90 °C

2.1: DMAP / acetonitrile / 2 h / 20 °C

With dmap; acetic acid; sodium nitrite; In acetonitrile;

DOI:10.1002/jhet.5570380202

Downstream raw materials:

4-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]benzeneisocyanate