phenyl benzyl ketene

Base Information

• Chemical Name: phenyl benzyl ketene
• CAS No.: 42955-17-9
• Molecular Formula: C₁₅H₁₂O
• Molecular Weight: 208.26
• Mol file: 42955-17-9.mol

Synonyms:phenyl benzyl ketene

Chemical Property of phenyl benzyl ketene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl benzyl ketene

There total 1 articles about phenyl benzyl ketene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-diphenylpropanoic acid (94942-89-9) → phenyl benzyl ketene (42955-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / 1.5 h / Inert atmosphere; Reflux

2: triethylamine / dichloromethane / 1 h / 22 °C / Inert atmosphere

With thionyl chloride; triethylamine; In dichloromethane;

DOI:10.1021/ja3103007

Reference yield:

phenyl benzyl ketene (42955-17-9) → Z-3-benzyl-4-(1,2-diphenylethylidene)-3-phenyloxetan-2-one

Guidance literature:

With tributylphosphine; In dichloromethane; at 0 - 20 ℃; for 5h; Reagent/catalyst; Temperature; Inert atmosphere;

DOI:10.1016/j.tet.2020.131838

Reference yield:

phenyl benzyl ketene (42955-17-9) + dimethyl azodicarboxylate (2446-84-6) → dimethyl (R)-3-benzyl-4-oxo-3-phenyl-1,2-diazetidine-1,2-dicarboxylate (1073529-39-1) + dimethyl (S)-3-benzyl-4-oxo-3-phenyl-1,2-diazetidine-1,2-dicarboxylate

Guidance literature:

With (R)-(+)-4-pyrrolidinopyrindinyl(pentamethylcyclopentadienyl)iron; In dichloromethane; at -20 ℃; for 2h; optical yield given as %ee;

DOI:10.1002/anie.200802439

upstream raw materials:

2,3-diphenylpropanoic acid

Downstream raw materials:

dimethyl (R)-3-benzyl-4-oxo-3-phenyl-1,2-diazetidine-1,2-dicarboxylate

(S)-perfluorophenyl 2-fluoro-2,3-diphenylpropanoate

C₁₂H₁₀NO₄S₂^(1-)*C₃₇H₄₀FFeN₂O⁽¹⁺⁾