3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl dihydrogen phosphate

Base Information

• Chemical Name: 3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl dihydrogen phosphate
• CAS No.: 92283-18-6
• Molecular Formula: C₈H₁₆NO₉P
• Molecular Weight: 301.19
• Mol file: 92283-18-6.mol

Synonyms:3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl dihydrogen phosphate

Chemical Property of 3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl dihydrogen phosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl dihydrogen phosphate

There total 3 articles about 3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl dihydrogen phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-acetyl-D-galactosamine (72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4,14215-68-0) + ATP (56-65-5,896506-78-8) → 3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl dihydrogen phosphate (92283-18-6,16503-17-6,25249-56-3,6866-69-9) + adenosine 5'-diphosphate (58-64-0,905904-58-7)

Guidance literature:

With recombinant galactokinase from Streptococcus pneumoniae TIGR₄; magnesium chloride; at 45 ℃; for 3h; pH=8; Time; Kinetics; aq. buffer; Enzymatic reaction;

DOI:10.1016/j.carres.2011.08.014

Reference yield:

2-amino-2-deoxy-α-D-galactopyranosyl 1-phosphate (2152-75-2,19889-76-0,22916-34-3,35946-79-3,26401-96-7) + S-acetyl coenzyme A (72-89-9) → 3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl dihydrogen phosphate (92283-18-6,16503-17-6,25249-56-3,6866-69-9)

Guidance literature:

With Pyrococcus furiosus enzyme; magnesium(II); In various solvent(s); at 80 ℃; for 0.666667h; pH=7.5;

DOI:10.1021/ja044117p

Reference yield:

→ 3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-α-D-galactopyranosyl dihydrogen phosphate (92283-18-6,16503-17-6,25249-56-3,6866-69-9)

Guidance literature:

2-Acetamido-2-desoxy-tetra-O-acetyl-β-D-galactopyranose, 1) H3PO4, 2) Verseifung des Rk.prod. mit 1n-LiOH (nach Mc Donald, J. Org. Chem. 27 <1962> 1107) ;

DOI:10.1021/jo01044a525

upstream raw materials:

2-amino-2-deoxy-α-D-galactopyranosyl 1-phosphate

S-acetyl coenzyme A

N-acetyl-D-galactosamine

ATP

Downstream raw materials:

uridine-5'-diphospho-N-acetyl-D-galactosamine