6--1-(ethoxymethyl)-5-isopropyluracil

Base Information

Chemical Name:6--1-(ethoxymethyl)-5-isopropyluracil
CAS No.:165960-81-6
Molecular Formula:C₂₁H₂₈N₂O₅
Molecular Weight:388.464
Hs Code.:

6-<acetoxy(3,5-dimethylphenyl)methyl>-1-(ethoxymethyl)-5-isopropyluracil

Synonyms:6--1-(ethoxymethyl)-5-isopropyluracil

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6--1-(ethoxymethyl)-5-isopropyluracil

Chemical Property:

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Technology Process of 6--1-(ethoxymethyl)-5-isopropyluracil

There total 4 articles about 6--1-(ethoxymethyl)-5-isopropyluracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5779-95-3
3,5-dimethylbenzaldehyde

: 165960-81-6
6--1-(ethoxymethyl)-5-isopropyluracil

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, -70 deg C, 1 h, 2.) THF, -70 deg C, 1 h

2: 35percent H₂O₂, 1N aq. NaOH / 1 h / Ambient temperature

3: pyridine / 12 h / Ambient temperature

With pyridine; sodium hydroxide; dihydrogen peroxide; lithium diisopropyl amide;
DOI:10.1021/jm00015a008

Reference yield:

: 144410-21-9
1-(ethoxymethyl)-5-isopropyl-2-thiouracil

: 165960-81-6
6--1-(ethoxymethyl)-5-isopropyluracil

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, -70 deg C, 1 h, 2.) THF, -70 deg C, 1 h

2: 35percent H₂O₂, 1N aq. NaOH / 1 h / Ambient temperature

3: pyridine / 12 h / Ambient temperature

With pyridine; sodium hydroxide; dihydrogen peroxide; lithium diisopropyl amide;
DOI:10.1021/jm00015a008

Reference yield:

: 1026164-38-4
6-[(3,5-Dimethyl-phenyl)-hydroxy-methyl]-1-ethoxymethyl-5-isopropyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

: 165960-81-6
6--1-(ethoxymethyl)-5-isopropyluracil

Guidance literature:: Multi-step reaction with 2 steps

1: 35percent H₂O₂, 1N aq. NaOH / 1 h / Ambient temperature

2: pyridine / 12 h / Ambient temperature

With pyridine; sodium hydroxide; dihydrogen peroxide;
DOI:10.1021/jm00015a008