{2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid ethyl ester

Base Information

• Chemical Name: {2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid ethyl ester
• CAS No.: 1155261-41-8
• Molecular Formula: C₂₀H₁₉N₃O₄
• Molecular Weight: 365.389
• Mol file: 1155261-41-8.mol

Synonyms:{2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid ethyl ester

Chemical Property of {2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of {2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid ethyl ester

There total 1 articles about {2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

Indole-2-carboxylic acid (1477-50-5,1228050-17-6) + (2-aminobenzoylamino)acetic acid ethyl ester (5973-34-2) → {2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid ethyl ester (1155261-41-8)

Guidance literature:

Indole-2-carboxylic acid; With phosphorus pentachloride; acetyl chloride; at 20 ℃; for 3.5h; Cooling with ice;

(2-aminobenzoylamino)acetic acid ethyl ester; With pyridine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.bmc.2009.02.012

Reference yield: 47.0%

{2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid ethyl ester (1155261-41-8) → {2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid (1155261-63-4)

Guidance literature:

{2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid ethyl ester; With potassium hydroxide; water; In tetrahydrofuran; at 20 ℃;

With hydrogenchloride; In water; at 0 ℃; pH=2 - 3;

DOI:10.1016/j.bmc.2009.02.012

upstream raw materials:

Indole-2-carboxylic acid

(2-aminobenzoylamino)acetic acid ethyl ester

Downstream raw materials:

{2-[(1H-indole-2-carbonyl)amino]benzoylamino}acetic acid