1,2,4,5-tetrafluoro-3-(phenylsulfonyl)-6-(trifluoromethyl)benzene

Base Information

• Chemical Name: 1,2,4,5-tetrafluoro-3-(phenylsulfonyl)-6-(trifluoromethyl)benzene
• CAS No.: 1548-85-2
• Molecular Formula: C₁₃H₅F₇O₂S
• Molecular Weight: 358.236
• Mol file: 1548-85-2.mol

Synonyms:1,2,4,5-tetrafluoro-3-(phenylsulfonyl)-6-(trifluoromethyl)benzene

Chemical Property of 1,2,4,5-tetrafluoro-3-(phenylsulfonyl)-6-(trifluoromethyl)benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2,4,5-tetrafluoro-3-(phenylsulfonyl)-6-(trifluoromethyl)benzene

There total 4 articles about 1,2,4,5-tetrafluoro-3-(phenylsulfonyl)-6-(trifluoromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

perfluorotoluene (434-64-0) + sodium benzenesulfonate (873-55-2) → 1,2,4,5-tetrafluoro-3-(phenylsulfonyl)-6-(trifluoromethyl)benzene (1548-85-2)

Guidance literature:

With sodium chloride; In water; acetone; at 20 ℃; for 24h; Micellar solution; Green chemistry;

DOI:10.1039/c7gc03514d

Reference yield:

1-phenylthio-4-trifluoromethyl-tetrafluoro-benzene (1548-86-3) → 1,2,4,5-tetrafluoro-3-(phenylsulfonyl)-6-(trifluoromethyl)benzene (1548-85-2)

Guidance literature:

With dihydrogen peroxide; acetic acid;

DOI:10.1039/jr9620001801

Reference yield:

perfluorotoluene (434-64-0) → 1,2,4,5-tetrafluoro-3-(phenylsulfonyl)-6-(trifluoromethyl)benzene (1548-85-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Py

2: aq. H₂O₂, AcOH

With pyridine; dihydrogen peroxide; acetic acid;

DOI:10.1039/jr9620001801

upstream raw materials:

1-phenylthio-4-trifluoromethyl-tetrafluoro-benzene

perfluorotoluene

potassium thiophenolate

sodium benzenesulfonate

Downstream raw materials:

2,3,5,6-Tetrafluor-4-benzolsulfonyl-benzoesaeure

Phenyl-<2,3,5,6-tetrafluor-phenyl>-sulfon