2-[4-CHLORO(PHENYLSULFONYL)ANILINO]ACETIC ACID

Base Information

• Chemical Name: 2-[4-CHLORO(PHENYLSULFONYL)ANILINO]ACETIC ACID
• CAS No.: 117309-41-8
• Molecular Formula: C₁₄H₁₂ClNO₄S
• Molecular Weight: 325.773
• Hs Code.: 2935009090
• Mol file: 117309-41-8.mol

Synonyms:NSC 626992

Chemical Property of 2-[4-CHLORO(PHENYLSULFONYL)ANILINO]ACETIC ACID

Chemical Property:

• Vapor Pressure: 2.76E-12mmHg at 25°C
• Melting Point: 161-162°
• Boiling Point: 535.2°Cat760mmHg
• Flash Point: 277.5°C
• PSA: 83.06000
• Density: 1.479g/cm³
• LogP: 3.70070
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-[4-Chloro(phenylsulfonyl)anilino]aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[4-CHLORO(PHENYLSULFONYL)ANILINO]ACETIC ACID

There total 2 articles about 2-[4-CHLORO(PHENYLSULFONYL)ANILINO]ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[Benzenesulfonyl-(4-chloro-phenyl)-amino]-acetic acid ethyl ester → [Benzenesulfonyl-(4-chloro-phenyl)-amino]-acetic acid (117309-41-8)

Guidance literature:

With sodium hydroxide; In ethanol; water; for 2h; Yield given; Heating;

DOI:10.1021/jm00121a027

Reference yield:

N-(4-chlorophenyl)benzenesulfonamide (4750-28-1) → [Benzenesulfonyl-(4-chloro-phenyl)-amino]-acetic acid (117309-41-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) NaH / 1) DMF, room temperature, 30 min.; 2) room temperature, overnight

2: NaOH / ethanol; H₂O / 2 h / Heating

With sodium hydroxide; sodium hydride; In ethanol; water;

DOI:10.1021/jm00121a027

upstream raw materials:

N-(4-chlorophenyl)benzenesulfonamide

Refernces