4-({[4-(methoxy)phenyl]methyl}amino)-4'-(trifluoromethyl)-3-biphenylcarbonitrile

Base Information

Chemical Name:4-({[4-(methoxy)phenyl]methyl}amino)-4'-(trifluoromethyl)-3-biphenylcarbonitrile
CAS No.:912953-79-8
Molecular Formula:C₂₂H₁₇F₃N₂O
Molecular Weight:382.385
Hs Code.:

Synonyms:4-({[4-(methoxy)phenyl]methyl}amino)-4'-(trifluoromethyl)-3-biphenylcarbonitrile

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Chemical Property of 4-({[4-(methoxy)phenyl]methyl}amino)-4'-(trifluoromethyl)-3-biphenylcarbonitrile

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Technology Process of 4-({[4-(methoxy)phenyl]methyl}amino)-4'-(trifluoromethyl)-3-biphenylcarbonitrile

There total 1 articles about 4-({[4-(methoxy)phenyl]methyl}amino)-4'-(trifluoromethyl)-3-biphenylcarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 405520-49-2
4-amino-4'-(trifluoromethyl)-3-biphenylcarbonitrile

: 824-94-2
p-methoxybenzyl chloride

: 912953-79-8
4-({[4-(methoxy)phenyl]methyl}amino)-4'-(trifluoromethyl)-3-biphenylcarbonitrile

Guidance literature:: With triethylamine; In acetonitrile; at 150 ℃; for 0.208333h; Microwave irradiation;

Reference yield: 89.0%

: 912953-79-8
4-({[4-(methoxy)phenyl]methyl}amino)-4'-(trifluoromethyl)-3-biphenylcarbonitrile

: 912953-80-1
[3-(aminomethyl)-4'-(trifluoromethyl)-4-biphenylyl]{[4-(methoxy)phenyl]methyl}amine

Guidance literature:: 4-({[4-(methoxy)phenyl]methyl}amino)-4'-(trifluoromethyl)-3-biphenylcarbonitrile; With lithium aluminium tetrahydride; In tetrahydrofuran; hexanes; at -50 - 20 ℃; for 1.5h;

With sodium hydroxide; water; In tetrahydrofuran; hexanes; at -50 ℃; for 0.5h;