N-<(4-Nitrophenyl-d4)thio>-7-tert-butyl-1-aminopyrene

Base Information

• Chemical Name: N-<(4-Nitrophenyl-d4)thio>-7-tert-butyl-1-aminopyrene
• CAS No.: 156268-49-4
• Molecular Formula: C₂₆H₂₂N₂O₂S
• Molecular Weight: 430.507
• Mol file: 156268-49-4.mol

Synonyms:N-<(4-Nitrophenyl-d4)thio>-7-tert-butyl-1-aminopyrene

Chemical Property of N-<(4-Nitrophenyl-d4)thio>-7-tert-butyl-1-aminopyrene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<(4-Nitrophenyl-d4)thio>-7-tert-butyl-1-aminopyrene

There total 6 articles about N-<(4-Nitrophenyl-d4)thio>-7-tert-butyl-1-aminopyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

4-Nitrobenzenesulfenyl-d4 chloride (156268-51-8) + 7-tert-Butyl-1-aminopyrene (156268-50-7) → N-<(4-Nitrophenyl-d4)thio>-7-tert-butyl-1-aminopyrene (156268-49-4)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 ℃; for 2h;

DOI:10.1021/jo00091a015

Reference yield:

2-(tert-butyl)pyrene (78751-62-9) → N-<(4-Nitrophenyl-d4)thio>-7-tert-butyl-1-aminopyrene (156268-49-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 56 percent / conc. HNO₃ / acetic acid / 1 h / 100 - 110 °C

2: 85 percent / H₂ / 5percent Pd/C / tetrahydrofuran; ethanol / 5 h / Ambient temperature

3: 49 percent / Et₃N / tetrahydrofuran / 2 h / 0 °C

With hydrogen; nitric acid; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetic acid;

DOI:10.1021/jo00091a015

Reference yield:

2-tert-butyl-6-nitropyrene (88829-61-2) → N-<(4-Nitrophenyl-d4)thio>-7-tert-butyl-1-aminopyrene (156268-49-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / H₂ / 5percent Pd/C / tetrahydrofuran; ethanol / 5 h / Ambient temperature

2: 49 percent / Et₃N / tetrahydrofuran / 2 h / 0 °C

With hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol;

DOI:10.1021/jo00091a015

upstream raw materials:

4-Nitrobenzenesulfenyl-d4 chloride

7-tert-Butyl-1-aminopyrene

chlorobenzene-d⁽⁵⁾

1-chloro-4-nitrobenzene-d4

Refernces