1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-(4-fluorobenzoyl)hydrazono)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

Base Information

Chemical Name:1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-(4-fluorobenzoyl)hydrazono)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
CAS No.:1340587-05-4
Molecular Formula:C₂₅H₂₃F₂N₅O₄
Molecular Weight:495.486
Hs Code.:

Synonyms:1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-(4-fluorobenzoyl)hydrazono)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

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Chemical Property of 1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-(4-fluorobenzoyl)hydrazono)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

Chemical Property:

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MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-(4-fluorobenzoyl)hydrazono)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

There total 2 articles about 1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-(4-fluorobenzoyl)hydrazono)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 1340587-15-6
C₁₀H₁₁FN₂O₂

: 85721-33-1,178489-05-9,189257-90-7
ciprofloxacin

: 1340587-05-4
1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-(4-fluorobenzoyl)hydrazono)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

Guidance literature:: With acetic acid; In acetonitrile; at 20 - 50 ℃; for 4.5h;
DOI:10.1016/j.ejmech.2011.07.052

Reference yield:

: 456-06-4
4-fluorobenzoyl hydrazide

: 1340587-05-4
1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-(4-fluorobenzoyl)hydrazono)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 0.17 h / 20 °C

2: acetic acid / acetonitrile / 4.5 h / 20 - 50 °C

With acetic acid; In acetonitrile;
DOI:10.1016/j.ejmech.2011.07.052