C₂₆H₂₇NO₃

Base Information

• Chemical Name: C₂₆H₂₇NO₃
• CAS No.: 1437656-93-3
• Molecular Formula: C₂₆H₂₇NO₃
• Molecular Weight: 401.505
• Mol file: 1437656-93-3.mol

Synonyms:C₂₆H₂₇NO₃

Chemical Property of C₂₆H₂₇NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₇NO₃

There total 7 articles about C₂₆H₂₇NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,5-tri-O-benzyl-4-deoxy-4-azido-D-xylose (1437656-83-1) → C26H27NO3 (1437656-93-3)

Guidance literature:

With trimethylphosphane; In methanol; toluene; at 0 ℃; for 1h;

DOI:10.1021/ol4012053

Reference yield:

2,3,5-tri-O-benzyl-L-arabinofuranose (96192-07-3) → C26H27NO3 (1437656-93-3)

Guidance literature:

Multi-step reaction with 7 steps

1: sodium tetrahydroborate / ethanol / 5 h / 0 - 20 °C

2: triethylamine; dmap / dichloromethane

3: pyridine / 22 h / 0 - 4 °C

4: sodium azide; 15-crown-5; tetra(n-butyl)ammonium hydrogensulfate / N,N-dimethyl-formamide / 120 h / 100 °C

5: toluene-4-sulfonic acid / methanol; chloroform / 3 h

6: Dess-Martin periodane / dichloromethane / 0 - 4 °C

7: trimethylphosphane / methanol; toluene / 1 h / 0 °C

With pyridine; dmap; sodium tetrahydroborate; sodium azide; 15-crown-5; tetra(n-butyl)ammonium hydrogensulfate; Dess-Martin periodane; toluene-4-sulfonic acid; triethylamine; trimethylphosphane; In methanol; ethanol; dichloromethane; chloroform; N,N-dimethyl-formamide; toluene;

DOI:10.1021/ol4012053

Reference yield:

(2S,3S,4S)-2,3,5-tri-O-benzyl-pentane-1,4-diol → C26H27NO3 (1437656-93-3)

Guidance literature:

Multi-step reaction with 6 steps

1: triethylamine; dmap / dichloromethane

2: pyridine / 22 h / 0 - 4 °C

3: sodium azide; 15-crown-5; tetra(n-butyl)ammonium hydrogensulfate / N,N-dimethyl-formamide / 120 h / 100 °C

4: toluene-4-sulfonic acid / methanol; chloroform / 3 h

5: Dess-Martin periodane / dichloromethane / 0 - 4 °C

6: trimethylphosphane / methanol; toluene / 1 h / 0 °C

With pyridine; dmap; sodium azide; 15-crown-5; tetra(n-butyl)ammonium hydrogensulfate; Dess-Martin periodane; toluene-4-sulfonic acid; triethylamine; trimethylphosphane; In methanol; dichloromethane; chloroform; N,N-dimethyl-formamide; toluene;

DOI:10.1021/ol4012053

upstream raw materials:

2,3,5-tri-O-benzyl-L-arabinofuranose

2,3,5-tri-O-benzyl-1-O-trityl-L-arabinitol

2,3,5-tri-O-benzyl-4-O-methanesulfonyl-1-O-trityl-L-arabinitol

2,3,5-tri-O-benzyl-4-deoxy-4-azido-1-O-trityl-D-xylitol

Downstream raw materials:

C₃₈H₄₆N₂O₅

C₃₈H₄₆N₂O₅

C₃₆H₄₄N₂O₅

C₃₆H₄₄N₂O₅