(+/-)-N-acetyl-2-aminodecanoic acid

Base Information

• Chemical Name: (+/-)-N-acetyl-2-aminodecanoic acid
• CAS No.: 78590-03-1
• Molecular Formula: C₁₂H₂₃NO₃
• Molecular Weight: 229.32
• Mol file: 78590-03-1.mol

Synonyms:(+/-)-N-acetyl-2-aminodecanoic acid

Chemical Property of (+/-)-N-acetyl-2-aminodecanoic acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (+/-)-N-acetyl-2-aminodecanoic acid

There total 5 articles about (+/-)-N-acetyl-2-aminodecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.1%

rac-2-aminodecanoic acid (17702-88-4) + acetic anhydride (108-24-7) → (+/-)-N-acetyl-2-aminodecanoic acid (78590-03-1,5440-41-5)

Guidance literature:

DOI:10.1021/jm00122a003

Reference yield:

2-acetylamino-2-cyano-decanoic acid ethyl ester (855212-43-0) → (+/-)-N-acetyl-2-aminodecanoic acid (78590-03-1,5440-41-5)

Guidance literature:

With sodium carbonate;

DOI:10.1021/ja01159a502

Reference yield:

2-bromodecanoic acid (2623-95-2) → (+/-)-N-acetyl-2-aminodecanoic acid (78590-03-1,5440-41-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 62.9 percent / 28percent aq. NH₃ / 168 h / Ambient temperature

2: 92.1 percent

With ammonium hydroxide;

DOI:10.1021/jm00122a003

upstream raw materials:

2-acetylamino-2-cyano-decanoic acid ethyl ester

acetylamino-octyl-malonic acid diethyl ester

rac-2-aminodecanoic acid

acetic anhydride

Downstream raw materials:

(S)-2-((S)-1-Carboxy-ethylamino)-decanoic acid benzyl ester

(4S)-1-benzyl-3-<(2S)-2-amino>propionyl>-2-oxoimidazolidine-4-carboxylic acid

(S)-1-Benzyl-3-[(S)-2-((S)-1-ethoxycarbonyl-nonylamino)-propionyl]-2-oxo-imidazolidine-4-carboxylic acid

benzyl (4S)-1-methyl-3-{(2S)-2-[N-((1S)-1-ethoxycarbonyl-n-nonyl)amino]propionyl}-2-oxo-imidazolidine-4-carboxylate