C₁₅H₁₄O₂

Base Information

• Chemical Name: C₁₅H₁₄O₂
• CAS No.: 1431371-17-3
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.275
• Mol file: 1431371-17-3.mol

Synonyms:C₁₅H₁₄O₂

Chemical Property of C₁₅H₁₄O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₁₄O₂

There total 1 articles about C₁₅H₁₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Benzyl propargyl ether (4039-82-1) + 2-iodo-cyclopent-2-enone (33948-35-5) → C15H14O2 (1431371-17-3)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/ol400628h

Reference yield: 75.0%

trimethyl[(3-methylbuta-1,3-dien-1-yl)oxy]silane (58274-64-9) + C15H14O2 (1431371-17-3) → C23H30O3Si + C23H30O3Si

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine; In toluene; at 190 ℃; for 0.333333h; Temperature; Microwave irradiation; Inert atmosphere;

DOI:10.1021/ol400628h

Reference yield:

C15H14O2 (1431371-17-3) → C36H50O6Si

Guidance literature:

Multi-step reaction with 10 steps

1.1: bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine / toluene / 0.33 h / 190 °C / Microwave irradiation; Inert atmosphere

2.1: 10 wt% Pd(OH)2 on carbon; hydrogen / isopropyl alcohol / 5 h / 20 °C

2.2: 15 h / 20 °C / Inert atmosphere

3.1: tert.-butylhydroperoxide; bis(acetylacetonate)oxovanadium / toluene; dichloromethane; decane / 2 h / 0 °C / Inert atmosphere; Molecular sieve

4.1: caesium carbonate / N,N-dimethyl-formamide / 4 h / 0 °C / Inert atmosphere

5.1: hydrogen / ethanol / 3 h / Reflux; Inert atmosphere

6.1: triethylamine; dmap / dichloromethane / 2 h / 20 °C / Inert atmosphere

7.1: bismuth(lll) trifluoromethanesulfonate / diethyl ether / 2 h / 0 °C / Inert atmosphere

8.1: indium; aluminium / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

8.2: 3 h / -30 °C / Inert atmosphere

9.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 6 h / 50 °C / Inert atmosphere

9.2: 1 h / 50 °C / Inert atmosphere

10.1: Amberlyst? 15 / toluene / 9 h / 50 °C / Inert atmosphere

With bismuth(lll) trifluoromethanesulfonate; tert.-butylhydroperoxide; dmap; bis-triphenylphosphine-palladium(II) chloride; indium; bis(acetylacetonate)oxovanadium; 10 wt% Pd(OH)2 on carbon; hydrogen; caesium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; 9-bora-bicyclo[3.3.1]nonane; aluminium; In tetrahydrofuran; diethyl ether; decane; ethanol; dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol; toluene; 1.1: |Diels-Alder Cycloaddition;

DOI:10.1021/ol400628h

upstream raw materials:

Benzyl propargyl ether

2-iodo-cyclopent-2-enone