(2S)-2-tert-butoxycarbonylamino-N-(2-hydroxy-(1R)-1-phenyl-ethyl)-succinamic acid benzyl ester

Base Information

• Chemical Name: (2S)-2-tert-butoxycarbonylamino-N-(2-hydroxy-(1R)-1-phenyl-ethyl)-succinamic acid benzyl ester
• CAS No.: 719308-03-9
• Molecular Formula: C₂₄H₂₈N₂O₆
• Molecular Weight: 440.496

Synonyms:(2S)-2-tert-butoxycarbonylamino-N-(2-hydroxy-(1R)-1-phenyl-ethyl)-succinamic acid benzyl ester

Chemical Property of (2S)-2-tert-butoxycarbonylamino-N-(2-hydroxy-(1R)-1-phenyl-ethyl)-succinamic acid benzyl ester

Chemical Property:

Purity/Quality:

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Technology Process of (2S)-2-tert-butoxycarbonylamino-N-(2-hydroxy-(1R)-1-phenyl-ethyl)-succinamic acid benzyl ester

There total 1 articles about (2S)-2-tert-butoxycarbonylamino-N-(2-hydroxy-(1R)-1-phenyl-ethyl)-succinamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S)-2-tert-butoxycarbonylamino-N-((2S)-2-hydroxy-1-phenyl-ethyl)-succinamic acid benzyl ester → (2S)-2-tert-butoxycarbonylamino-N-(2-hydroxy-(1R)-1-phenyl-ethyl)-succinamic acid benzyl ester (719308-03-9)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

(2S)-2-tert-butoxycarbonylamino-N-(2-hydroxy-(1R)-1-phenyl-ethyl)-succinamic acid benzyl ester (719308-03-9) → (2S)-2-tert-butoxycarbonylamino-3-(4-phenyl-oxazol-2-yl)-propionic acid benzyl ester (719308-12-0)

Guidance literature:

With iodine; triethylamine; triphenylphosphine; In tetrahydrofuran; at -78 - 20 ℃; for 3h;

Downstream raw materials:

(2S)-2-tert-butoxycarbonylamino-3-(4-phenyl-oxazol-2-yl)-propionic acid benzyl ester

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