Technology Process of C28H29N7O4
There total 9 articles about C28H29N7O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
for 2h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl acetamide / 16 h / 100 °C
2: 4 h
3: magnesium sulfate / N,N-dimethyl acetamide; acetonitrile / 80 °C
4: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h
With
magnesium sulfate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl acetamide; N,N-dimethyl-formamide; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: dichloromethane / 3 h / 20 °C
2.1: triethylamine / tetrahydrofuran / 0.25 h / 20 °C
2.2: 20 °C
3.1: hydrogen / 5 % platinum on carbon / tetrahydrofuran
4.1: hydrogenchloride / 1,4-dioxane / 60 °C
5.1: magnesium sulfate / N,N-dimethyl acetamide; acetonitrile / 80 °C
6.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h
With
hydrogenchloride; hydrogen; magnesium sulfate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; N-ethyl-N,N-diisopropylamine;
5 % platinum on carbon;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl acetamide; N,N-dimethyl-formamide; acetonitrile;