(R)-N-4-(trifluoromethoxy)benzyl 2-(benzyloxycarbonyl)amino-3-hydroxypropionamide

Base Information

Chemical Name:(R)-N-4-(trifluoromethoxy)benzyl 2-(benzyloxycarbonyl)amino-3-hydroxypropionamide
CAS No.:1197982-98-1
Molecular Formula:C₁₉H₁₉F₃N₂O₅
Molecular Weight:412.365
Hs Code.:

Synonyms:(R)-N-4-(trifluoromethoxy)benzyl 2-(benzyloxycarbonyl)amino-3-hydroxypropionamide

Suppliers and Price of (R)-N-4-(trifluoromethoxy)benzyl 2-(benzyloxycarbonyl)amino-3-hydroxypropionamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-N-4-(trifluoromethoxy)benzyl 2-(benzyloxycarbonyl)amino-3-hydroxypropionamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-N-4-(trifluoromethoxy)benzyl 2-(benzyloxycarbonyl)amino-3-hydroxypropionamide

There total 3 articles about (R)-N-4-(trifluoromethoxy)benzyl 2-(benzyloxycarbonyl)amino-3-hydroxypropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 6081-61-4
N-(benzyloxycarbonyl)-D-serine

: 93919-56-3
4-(trifluoromethoxy)benzyl amine

: 1197982-98-1
(R)-N-4-(trifluoromethoxy)benzyl 2-(benzyloxycarbonyl)amino-3-hydroxypropionamide

Guidance literature:: N-(benzyloxycarbonyl)-D-serine; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

4-(trifluoromethoxy)benzyl amine; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1021/jm901563p

Reference yield:

: 102988-98-7
C₁₆H₂₁NO₇

: 93919-56-3
4-(trifluoromethoxy)benzyl amine

: 1197982-98-1
(R)-N-4-(trifluoromethoxy)benzyl 2-(benzyloxycarbonyl)amino-3-hydroxypropionamide

Guidance literature:: In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

Reference yield:

: 6081-61-4
N-(benzyloxycarbonyl)-D-serine

: 1197982-98-1
(R)-N-4-(trifluoromethoxy)benzyl 2-(benzyloxycarbonyl)amino-3-hydroxypropionamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 4-methyl-morpholine / tetrahydrofuran / -78 °C / Inert atmosphere

1.2: -78 °C / Inert atmosphere

2.1: tetrahydrofuran / -78 - 20 °C / Inert atmosphere

With 4-methyl-morpholine; In tetrahydrofuran;