C₁₉H₂₈O₃

Base Information

• Chemical Name: C₁₉H₂₈O₃
• CAS No.: 1615239-64-9
• Molecular Formula: C₁₉H₂₈O₃
• Molecular Weight: 304.43
• Mol file: 1615239-64-9.mol

Synonyms:C₁₉H₂₈O₃

Chemical Property of C₁₉H₂₈O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₂₈O₃

There total 1 articles about C₁₉H₂₈O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

butyraldehyde (123-72-8) + (E)-tert-butyl 5-phenyl-pent-4-enoate (910869-99-7) → C19H28O3 (1615239-64-9)

Guidance literature:

(E)-tert-butyl 5-phenyl-pent-4-enoate; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

butyraldehyde; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

DOI:10.1021/ol501010k

Reference yield:

C19H28O3 (1615239-64-9) → tert-butyl 2-cinnamyl-3-oxohexanoate (1615239-79-6)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol501010k

Reference yield:

C19H28O3 (1615239-64-9) → tert-butyl 6-phenyl-2-propylnicotinate (1615240-59-9)

Guidance literature:

Multi-step reaction with 5 steps

1: Dess-Martin periodane / dichloromethane / 20 °C / Inert atmosphere

2: hydroxylamine hydrochloride; pyridine / Inert atmosphere

3: pyridine / 20 h / Inert atmosphere

4: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 3 h / 20 °C / Inert atmosphere

5: 1,8-diazabicyclo[5.4.0]undec-7-ene / chlorobenzene / 130 °C / Inert atmosphere

With pyridine; hydroxylamine hydrochloride; Dess-Martin periodane; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; chlorobenzene; 1: |Dess-Martin Oxidation;

DOI:10.1021/ol501010k

upstream raw materials:

butyraldehyde

(E)-tert-butyl 5-phenyl-pent-4-enoate

Downstream raw materials:

tert-butyl 2-cinnamyl-3-propyl-2H-azirine-2-carboxylate

tert-butyl 6-phenyl-2-propylnicotinate

tert-butyl 2-cinnamyl-3-oxohexanoate

C₁₉H₂₇NO₃