Technology Process of N12-benzyl-N1,N23-diformyl-N4,N8,N16,N20-tetratosyl-4,8,12,16,20-pentaaza-1,23-tricosanediamine
There total 8 articles about N12-benzyl-N1,N23-diformyl-N4,N8,N16,N20-tetratosyl-4,8,12,16,20-pentaaza-1,23-tricosanediamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 99 percent / sodium hydrogen carbonate / acetonitrile / 70 h / 70 °C
2: 99 percent / potassium carbonate / dimethylformamide / 144 h / 20 °C
3: 76 percent / hydrazine hydrate / 48 h / 75 °C
4: aq. HCl / CHCl3 / 4 h / 70 °C
5: 1.27 g / pyridine / 12 h / 20 °C
6: 85 percent / potassium carbonate / dimethylformamide / 96 h / 20 °C
7: 90 percent / hydrazine hydrate / 48 h / 75 °C
With
pyridine; hydrogenchloride; sodium hydrogencarbonate; potassium carbonate; hydrazine hydrate;
In
chloroform; N,N-dimethyl-formamide; acetonitrile;
1: Alkylation / 2: Alkylation / 3: Formylation / 4: Hydrolysis / 5: Tosylation / 6: Alkylation / 7: Formylation;
DOI:10.1246/bcsj.73.693
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 99 percent / potassium carbonate / dimethylformamide / 144 h / 20 °C
2: 76 percent / hydrazine hydrate / 48 h / 75 °C
3: aq. HCl / CHCl3 / 4 h / 70 °C
4: 1.27 g / pyridine / 12 h / 20 °C
5: 85 percent / potassium carbonate / dimethylformamide / 96 h / 20 °C
6: 90 percent / hydrazine hydrate / 48 h / 75 °C
With
pyridine; hydrogenchloride; potassium carbonate; hydrazine hydrate;
In
chloroform; N,N-dimethyl-formamide;
1: Alkylation / 2: Formylation / 3: Hydrolysis / 4: Tosylation / 5: Alkylation / 6: Formylation;
DOI:10.1246/bcsj.73.693
