C₄₁H₄₇NO₄S

Base Information

• Chemical Name: C₄₁H₄₇NO₄S
• CAS No.: 1370028-21-9
• Molecular Formula: C₄₁H₄₇NO₄S
• Molecular Weight: 649.894
• Mol file: 1370028-21-9.mol

Synonyms:C₄₁H₄₇NO₄S

Chemical Property of C₄₁H₄₇NO₄S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₁H₄₇NO₄S

There total 1 articles about C₄₁H₄₇NO₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

C33H36O3 + N,S-dimethyl-S-phenylsulfoximine (33993-53-2) → C41H47NO4S (1370028-19-5) + C41H47NO4S (1370028-20-8) + C41H47NO4S (1370028-21-9) + C41H47NO4S (1370028-22-0)

Guidance literature:

N,S-dimethyl-S-phenylsulfoximine; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h; Inert atmosphere;

C₃₃H₃₆O₃; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

DOI:10.1248/cpb.60.137

Reference yield: 90.0%

C41H47NO4S (1370028-21-9) → C33H36O3 (1370028-14-0)

Guidance literature:

In toluene; at 120 ℃; for 7.5h; Inert atmosphere;

DOI:10.1248/cpb.60.137

Reference yield:

C41H47NO4S (1370028-21-9) → C49H66O3

Guidance literature:

Multi-step reaction with 12 steps

1.1: toluene / 7.5 h / 120 °C / Inert atmosphere

2.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere

2.2: -78 °C / Inert atmosphere

3.1: Crabtree's catalyst; hydrogen / dichloromethane / 48 h / 20 °C / Inert atmosphere

4.1: trimethylaluminum / hexane; dichloromethane / 0.5 h / 0 °C / Inert atmosphere

4.2: 1 h / 0 °C / Inert atmosphere

5.1: tert.-butyl lithium / tetrahydrofuran; diethyl ether; pentane / 0.67 h / -78 °C / Inert atmosphere

5.2: 1.5 h / Inert atmosphere

6.1: zinc(II) chloride / dichloromethane / 0 - 20 °C / Inert atmosphere

7.1: lithium aluminium tetrahydride / diethyl ether / 0.25 h / 0 °C / Inert atmosphere

8.1: sodium hydride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

9.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C / Inert atmosphere

9.2: 0.08 h / 0 °C / Inert atmosphere

10.1: 0.5 h / 0 °C / Inert atmosphere

11.1: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / toluene / 0.5 h / 90 °C / Inert atmosphere

12.1: bromocatecholborane / dichloromethane / 1 h / -78 °C / Inert atmosphere

With lithium aluminium tetrahydride; n-butyllithium; Crabtree's catalyst; 2,2'-azobis(isobutyronitrile); bromocatecholborane; hydrogen; trimethylaluminum; tert.-butyl lithium; tri-n-butyl-tin hydride; sodium hexamethyldisilazane; sodium hydride; N-ethyl-N,N-diisopropylamine; zinc(II) chloride; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; toluene; pentane; 6.1: Diels-Alder reaction;

DOI:10.1248/cpb.60.137

upstream raw materials:

N,S-dimethyl-S-phenylsulfoximine

Downstream raw materials:

C₅₁H₇₀O₄

C₄₉H₆₄O₃

C₅₀H₆₆O₂

C₁₉H₂₆O₃