N-{3-[2-(1-cyclopropylpiperidin-4-yl)-5-(2-methylpyridin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide

Base Information

Chemical Name:N-{3-[2-(1-cyclopropylpiperidin-4-yl)-5-(2-methylpyridin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide
CAS No.:1394939-68-4
Molecular Formula:C₃₁H₃₁F₃N₄O₃S₂
Molecular Weight:628.739
Hs Code.:

Synonyms:N-{3-[2-(1-cyclopropylpiperidin-4-yl)-5-(2-methylpyridin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide

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Chemical Property of N-{3-[2-(1-cyclopropylpiperidin-4-yl)-5-(2-methylpyridin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide

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Technology Process of N-{3-[2-(1-cyclopropylpiperidin-4-yl)-5-(2-methylpyridin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide

There total 1 articles about N-{3-[2-(1-cyclopropylpiperidin-4-yl)-5-(2-methylpyridin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

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: 1394939-47-9
N-{3-[5-(2-chloropyridin-4-yl)-2-(1-cyclopropylpiperidin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide

: 75-24-1
trimethylaluminum

: 1394939-68-4
N-{3-[2-(1-cyclopropylpiperidin-4-yl)-5-(2-methylpyridin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide

Guidance literature:: N-{3-[5-(2-chloropyridin-4-yl)-2-(1-cyclopropylpiperidin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide; trimethylaluminum; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; hexane; at 105 ℃; for 2h; Inert atmosphere;

With sodium hydrogencarbonate; In 1,4-dioxane; hexane; water; ethyl acetate;