Technology Process of C20H27NO2
There total 4 articles about C20H27NO2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
platinum(IV) oxide; hydrogen;
In
methanol;
at 20 ℃;
for 24h;
stereoselective reaction;
DOI:10.1021/ol2030058
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 0.33 h / -40 °C
1.2: 3.17 h / -40 - 40 °C
2.1: isobutyric Acid / toluene / 24 h / Reflux
3.1: platinum(IV) oxide; hydrogen / methanol / 24 h / 20 °C
With
platinum(IV) oxide; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; isobutyric Acid;
In
methanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol2030058
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.33 h / 0 °C
1.2: 5 h / 0 - 20 °C
2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 0.33 h / -40 °C
2.2: 3.17 h / -40 - 40 °C
3.1: isobutyric Acid / toluene / 24 h / Reflux
4.1: platinum(IV) oxide; hydrogen / methanol / 24 h / 20 °C
With
platinum(IV) oxide; hydrogen; sodium hexamethyldisilazane; 1,8-diazabicyclo[5.4.0]undec-7-ene; isobutyric Acid;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol2030058