5,6-oxido-3β,20β-dihydroxypregnane dibenzoate

Base Information

• Chemical Name: 5,6-oxido-3β,20β-dihydroxypregnane dibenzoate
• CAS No.: 75851-45-5
• Molecular Formula: C₃₅H₄₂O₅
• Molecular Weight: 542.715
• Mol file: 75851-45-5.mol

Synonyms:5,6-oxido-3β,20β-dihydroxypregnane dibenzoate

Chemical Property of 5,6-oxido-3β,20β-dihydroxypregnane dibenzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 5,6-oxido-3β,20β-dihydroxypregnane dibenzoate

There total 1 articles about 5,6-oxido-3β,20β-dihydroxypregnane dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3β,20β-dihydroxypregn-5-ene dibenzoate (72420-14-5) → 5,6-oxido-3β,20β-dihydroxypregnane dibenzoate (75851-45-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; Ambient temperature;

DOI:10.1021/ja00392a034

Reference yield: 65.0%

5,6-oxido-3β,20β-dihydroxypregnane dibenzoate (75851-45-5) → 6β-chloro-3β,5α,20β-trihydroxypregnane 3,20-dibenzoate (75851-46-6)

Guidance literature:

With hydrogenchloride; In acetone; for 0.5h; Ambient temperature;

DOI:10.1021/ja00392a034

Reference yield:

5,6-oxido-3β,20β-dihydroxypregnane dibenzoate (75851-45-5) → 6β-chloro-3β,20β-dihydroxypregn-4-ene dibenzoate (75851-47-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / 37percent HCl / acetone / 0.5 h / Ambient temperature

2: 80 percent / SOCl₂ / pyridine / 0.5 h / 0 °C

With hydrogenchloride; thionyl chloride; In pyridine; acetone;

DOI:10.1021/ja00392a034

upstream raw materials:

3β,20β-dihydroxypregn-5-ene dibenzoate

Downstream raw materials:

6β-chloro-3β,5α,20β-trihydroxypregnane 3,20-dibenzoate

6β-chloro-3β,20β-dihydroxypregn-4-ene dibenzoate