1-(2-Methyl-5-nitrophenyl)hydrazine hydrochloride

Base Information

• Chemical Name: 1-(2-Methyl-5-nitrophenyl)hydrazine hydrochloride
• CAS No.: 5089-08-7
• Molecular Formula: C₇H₉N₃O₂
• Molecular Weight: 167.167
• DSSTox Substance ID: DTXSID20586210
• Mol file: 5089-08-7.mol

Synonyms:1-(2-METHYL-5-NITROPHENYL)HYDRAZINE HYDROCHLORIDE;(2-methyl-5-nitrophenyl)hydrazine;hydrochloride;DTXSID20586210;AKOS001476034;MCULE-4232133872;(2-METHYL-5-NITROPHENYL)HYDRAZINE HYDROCHLORIDE;(2-Methyl-5-nitrophenyl)hydrazine--hydrogen chloride (1/1)

Chemical Property of 1-(2-Methyl-5-nitrophenyl)hydrazine hydrochloride

Chemical Property:

• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 203.0461543
• Heavy Atom Count: 13
• Complexity: 169

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Methyl-5-nitrophenyl)hydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(C=C(C=C1)[N+](=O)[O-])NN.Cl

Technology Process of 1-(2-Methyl-5-nitrophenyl)hydrazine hydrochloride

There total 4 articles about 1-(2-Methyl-5-nitrophenyl)hydrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-methyl-5-nitroaniline (99-55-8) → (2-methyl-5-nitrophenyl)hydrazine (5089-08-7)

Guidance literature:

2-methyl-5-nitroaniline; With hydrogenchloride; sodium nitrite; In water; at 0 - 5 ℃;

With hydrogenchloride; stannous chloride hydrate; In water; at 0 - 5 ℃; for 0.5h;

DOI:10.1016/j.bmc.2015.04.083

Reference yield:

2-methyl-5-nitrophenylhydrazine hydrochloride → (2-methyl-5-nitrophenyl)hydrazine (5089-08-7)

Guidance literature:

With hydrogenchloride; tin(II) chloride dihdyrate; In water; at 0 - 10 ℃;

Reference yield:

→ (2-methyl-5-nitrophenyl)hydrazine (5089-08-7)

Guidance literature:

2-Methyl-5-nitro-anilin, analog Bischler, B. 2 <1889> 2801;

upstream raw materials:

2-methyl-5-nitroaniline

Downstream raw materials:

4-Nitro-3,3,7-trimethyl-2-(2-hydroxy-3-nitrostyryl)indolenine

4-Nitro-3,3,7-trimethyl-2-(2-hydroxy-5-nitrostyryl)indolenine

4-Nitro-3,3,7-trimethyl-2-(2-hydroxy-3-bromo-5-nitrostyryl)indolenine

4-Nitro-3,3,7-trimethyl-2-(2-hydroxy-3-methoxy-5-nitrostyryl)indolenine