2-(Bis(2-chloroethyl)amino)-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one

Base Information

Chemical Name:2-(Bis(2-chloroethyl)amino)-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one
CAS No.:156454-77-2
Molecular Formula:C₁₁H₁₃Cl₂N₂O₂P
Molecular Weight:307.116
Hs Code.:
DSSTox Substance ID:DTXSID50935459
Nikkaji Number:J582.950J

Synonyms:2-(Bis(2-chloroethyl)amino)-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one;156454-77-2;2,3-Dihydro-2-(bis(2-chloroethyl)amino)-4H-1,3,2-benzoxazaphosphorin-4-one;4H-1,3,2-Benzoxazaphosphorin-4-one, 2,3-dihydro-2-(bis(2-chloroethyl)amino)-;DTXSID50935459;LS-41603;2-[Bis(2-chloroethyl)amino]-2H-1,3,2-benzoxazaphosphinin-4-ol;2-[Bis(2-chloroethyl)amino]-2H-1,3,2-benzoxazaphosphorin-4(3H)-one

Suppliers and Price of 2-(Bis(2-chloroethyl)amino)-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(Bis(2-chloroethyl)amino)-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:306.0091700
Heavy Atom Count:18
Complexity:290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)NP(O2)N(CCCl)CCCl

Technology Process of 2-(Bis(2-chloroethyl)amino)-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one

There total 3 articles about 2-(Bis(2-chloroethyl)amino)-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 334-22-5
N,N-bis(chloro-2-ethyl)amine

: 99026-49-0
2-chloro-2,3-dihydro-4H-1,3,2-benzoxazaphosphorin-4-one

: 156454-77-2
2--2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one

Guidance literature:: DOI:10.1002/ardp.19943270408

Reference yield: 38.0%

: 821-48-7
bis-(2-chloroethyl)amine hydrochloride

: 99026-49-0
2-chloro-2,3-dihydro-4H-1,3,2-benzoxazaphosphorin-4-one

: 156454-77-2
2--2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one

Guidance literature:: With TEA; In tetrahydrofuran; for 12h; Heating;
DOI:10.1002/ardp.19943270408

Reference yield:

: 65-45-2
salicylamide

: 156454-77-2
2--2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / PCl₃ / toluene / 6 h / Heating

2: 38 percent / TEA / tetrahydrofuran / 12 h / Heating

With TEA; phosphorus trichloride; In tetrahydrofuran; toluene;
DOI:10.1002/ardp.19943270408