5-methylphenyl-1,3,7,9-tetramethylpyrido[2,3-d:6,5-d]dipyrimidine-2,4,6,8-tetrone

Base Information

• Chemical Name: 5-methylphenyl-1,3,7,9-tetramethylpyrido[2,3-d:6,5-d]dipyrimidine-2,4,6,8-tetrone
• CAS No.: 73029-31-9
• Molecular Formula: C₂₀H₁₉N₅O₄
• Molecular Weight: 393.402
• Mol file: 73029-31-9.mol

Synonyms:5-methylphenyl-1,3,7,9-tetramethylpyrido[2,3-d:6,5-d]dipyrimidine-2,4,6,8-tetrone

Chemical Property of 5-methylphenyl-1,3,7,9-tetramethylpyrido[2,3-d:6,5-d]dipyrimidine-2,4,6,8-tetrone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-methylphenyl-1,3,7,9-tetramethylpyrido[2,3-d:6,5-d]dipyrimidine-2,4,6,8-tetrone

There total 3 articles about 5-methylphenyl-1,3,7,9-tetramethylpyrido[2,3-d:6,5-d]dipyrimidine-2,4,6,8-tetrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1,3-dimethylbarbituric acid (769-42-6) + 4-methyl-benzaldehyde (104-87-0) → 5-methylphenyl-1,3,7,9-tetramethylpyrido[2,3-d:6,5-d]dipyrimidine-2,4,6,8-tetrone (73029-31-9)

Guidance literature:

With zirconium(IV) hydrogenphosphate monohydrate; ammonium acetate; In neat (no solvent); at 80 ℃; for 2h; Green chemistry;

DOI:10.2174/1570178611666140124002242

Reference yield: 50.0%

6-Amino-1,3-dimethylbarbituric acid (6642-31-5) + 4-methyl-benzaldehyde (104-87-0) → 5-methylphenyl-1,3,7,9-tetramethylpyrido[2,3-d:6,5-d]dipyrimidine-2,4,6,8-tetrone (73029-31-9) + 1-(4-methylphenyl)-1-bis(6-amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimid-5-yl)methane (73038-86-5)

Guidance literature:

toluene-4-sulfonic acid; In various solvent(s); at 100 ℃; for 4h;

DOI:10.1016/j.tet.2006.12.043

Reference yield:

→ 5-methylphenyl-1,3,7,9-tetramethylpyrido[2,3-d:6,5-d]dipyrimidine-2,4,6,8-tetrone (73029-31-9)

Guidance literature:

Bisuracilmethan Ib, Δ;

upstream raw materials:

6-Amino-1,3-dimethylbarbituric acid

4-methyl-benzaldehyde

1,3-dimethylbarbituric acid