O-(4-methoxycarbonylphenyl) N-methyl-N-phenyl thiocarbamate

Base Information

• Chemical Name: O-(4-methoxycarbonylphenyl) N-methyl-N-phenyl thiocarbamate
• CAS No.: 1258328-04-9
• Molecular Formula: C₁₆H₁₅NO₃S
• Molecular Weight: 301.366
• Mol file: 1258328-04-9.mol

Synonyms:O-(4-methoxycarbonylphenyl) N-methyl-N-phenyl thiocarbamate

Chemical Property of O-(4-methoxycarbonylphenyl) N-methyl-N-phenyl thiocarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-(4-methoxycarbonylphenyl) N-methyl-N-phenyl thiocarbamate

There total 3 articles about O-(4-methoxycarbonylphenyl) N-methyl-N-phenyl thiocarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

thiophosgene (463-71-8) + methyl 4-hydroxylbenzoate (99-76-3,156291-94-0) + N-methylaniline (100-61-8) → O-(4-methoxycarbonylphenyl) N-methyl-N-phenyl thiocarbamate (1258328-04-9)

Guidance literature:

thiophosgene; methyl 4-hydroxylbenzoate; With pyridine; In dichloromethane; at 0 - 20 ℃;

N-methylaniline; In dichloromethane; for 0.166667h;

DOI:10.1002/chem.201002303

Reference yield: 71.0%

Chlorthionameisensaeure-p-methoxycarbonylphenylester (10506-31-7) + N-methylaniline (100-61-8) → O-(4-methoxycarbonylphenyl) N-methyl-N-phenyl thiocarbamate (1258328-04-9)

Guidance literature:

In dichloromethane; for 0.166667h;

DOI:10.1021/jo102467j

Reference yield:

methyl 4-hydroxylbenzoate (99-76-3,156291-94-0) → O-(4-methoxycarbonylphenyl) N-methyl-N-phenyl thiocarbamate (1258328-04-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 0.25 h / 0 - 20 °C

2: dichloromethane / 0.17 h

With pyridine; In dichloromethane;

DOI:10.1021/jo102467j

upstream raw materials:

thiophosgene

methyl 4-hydroxylbenzoate

N-methylaniline

Chlorthionameisensaeure-p-methoxycarbonylphenylester

Downstream raw materials:

4-methoxycarbonyl-N-methyl-N-phenylbenzamide