cyclopropanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide

Base Information

• Chemical Name: cyclopropanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide
• CAS No.: 1026280-35-2
• Molecular Formula: C₁₇H₁₄N₄O₃
• Molecular Weight: 322.323
• Mol file: 1026280-35-2.mol

Synonyms:cyclopropanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide

Chemical Property of cyclopropanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclopropanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide

There total 3 articles about cyclopropanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → cyclopropanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide (1026280-35-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 47 percent / polyphosphoric acid / xylene / 60 - 150 °C

2: pyridine / 3 h / 20 °C

With pyridine; PPA; In xylene;

DOI:10.1016/j.ejmech.2006.03.014

Reference yield:

4-Nitrophenylene-1,2-diamine (99-56-9) → cyclopropanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide (1026280-35-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 47 percent / polyphosphoric acid / xylene / 60 - 150 °C

2: pyridine / 3 h / 20 °C

With pyridine; PPA; In xylene;

DOI:10.1016/j.ejmech.2006.03.014

Reference yield:

cyclopropanecarboxylic acid chloride (4023-34-1) + 5(6)-nitro 2-(4-aminophenyl)-1H-benzimidazole (71002-88-5) → cyclopropanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide (1026280-35-2)

Guidance literature:

With pyridine; at 20 ℃; for 3h;

DOI:10.1016/j.ejmech.2006.03.014

upstream raw materials:

cyclopropanecarboxylic acid chloride

5⁽⁶⁾-nitro 2-(4-aminophenyl)-1H-benzimidazole

4-amino-benzoic acid

4-Nitrophenylene-1,2-diamine

Downstream raw materials:

cyclopropanecarboxylic acid [4-(5-amino-1H-benzoimidazol-2-yl)-phenyl]-amide