5-Cfdru

Base Information

Chemical Name:5-Cfdru
CAS No.:55612-15-2
Molecular Formula:C₉H₁₀ClFN₂O₅
Molecular Weight:280.64
Hs Code.:
DSSTox Substance ID:DTXSID20970953
Mol file:55612-15-2.mol

Synonyms:5-CFDRU;5-chloro-1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)uracil;5-chloro-1-(2'-fluoro-2'-deoxyribofuranosyl)uracil;5-chloro-1-(2'-fluoro-2'-deoxyribofuranosyl)uracil, 14C-labeled

Suppliers and Price of 5-Cfdru

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 5-Cfdru

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：104.55000
Density:1.73g/cm³
LogP:-1.22130
XLogP3:-0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:280.0262273
Heavy Atom Count:18
Complexity:418

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)F)Cl
Isomeric SMILES:C1=C(C(=O)NC(=O)N1C2[C@@H]([C@@H]([C@H](O2)CO)O)F)Cl

Technology Process of 5-Cfdru

There total 3 articles about 5-Cfdru which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-chloro-6-O-acetyl-5,6-dihydro-1-(2'-fluoro-2'-deoxy-β-D-ribofuranosyl)uracil

: 55612-15-2
5-chloro-1-(2'-fluoro-2'-deoxy-β-D-ribofuranosyl)uracil

Guidance literature:: With ammonium hydroxide; In methanol; for 18h;
DOI:10.1021/jm00387a015

Reference yield:

: 56287-17-3,69123-94-0,784-71-4
2'-deoxy-2'-fluorouridine

: 55612-15-2
5-chloro-1-(2'-fluoro-2'-deoxy-β-D-ribofuranosyl)uracil

Guidance literature:: Multi-step reaction with 2 steps

1: Cl₂ / 0.17 h / Ambient temperature

2: conc. NH₄OH / methanol / 18 h

With ammonium hydroxide; chlorine; In methanol;
DOI:10.1021/jm00387a015