Acetic acid, 2-[(5-chloro-2-pyridinyl)oxy]-

Base Information

Chemical Name:Acetic acid, 2-[(5-chloro-2-pyridinyl)oxy]-
CAS No.:79674-59-2
Molecular Formula:C₇H₆ClNO₃
Molecular Weight:187.583
Hs Code.:
European Community (EC) Number:825-334-1
Mol file:79674-59-2.mol

Synonyms:79674-59-2;2-((5-chloropyridin-2-yl)oxy)acetic acid;Acetic acid, 2-[(5-chloro-2-pyridinyl)oxy]-;2-(5-chloropyridin-2-yl)oxyacetic acid;2-[(5-chloropyridin-2-yl)oxy]acetic acid;SCHEMBL208775;AKOS006295601;2-((5-chloropyridin-2-yl)oxy)aceticacid;2-[(5-Chloro-2-pyridinyl)oxy]acetic acid;CS-0231177;F88532;EN300-1073081

Suppliers and Price of Acetic acid, 2-[(5-chloro-2-pyridinyl)oxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 7 raw suppliers

Chemical Property of Acetic acid, 2-[(5-chloro-2-pyridinyl)oxy]-

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:187.0036207
Heavy Atom Count:12
Complexity:165

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=NC=C1Cl)OCC(=O)O

Technology Process of Acetic acid, 2-[(5-chloro-2-pyridinyl)oxy]-

There total 2 articles about Acetic acid, 2-[(5-chloro-2-pyridinyl)oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.9%

: 63305-94-2
ethyl 2-((5-chloropyridin-2-yl)oxy)acetate

: 79674-59-2
2-((5-chloropyridin-2-yl)oxy)acetic acid

Guidance literature:: With lithium hydroxide monohydrate; In dichloromethane; water; at 0 - 20 ℃; for 6h;

Reference yield:

: 4214-79-3
5-chloro-2-pyridinol

: 79674-59-2
2-((5-chloropyridin-2-yl)oxy)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 165 °C

2: ethanol; aqueous NaOH-solution

With sodium hydroxide; ethanol;
DOI:10.1021/jo01105a007

Reference yield: 70.6%

: 79674-59-2
2-((5-chloropyridin-2-yl)oxy)acetic acid

: 3-[3-(4-chlorophenoxy)pyrrolidin-1-yl]bicyclo[1.1.1]pentan-1-amine hydrochloride

: N-(3-(3-(4-chlorophenoxy)pyrrolidin-1-yl)bicyclo[1.1.1 ]pentan-1 yl)-2-((5-chloropyridin-2-yl)oxy)acetamide

Guidance literature:: 2-((5-chloropyridin-2-yl)oxy)acetic acid; With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine; In dichloromethane; ethyl acetate; at 0 ℃; for 0.166667h;

3-[3-(4-chlorophenoxy)pyrrolidin-1-yl]bicyclo[1.1.1]pentan-1-amine hydrochloride; In dichloromethane; ethyl acetate; at 0 - 20 ℃; for 2h;