Technology Process of C29H26F3N3O4
There total 11 articles about C29H26F3N3O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine; HATU;
In
dichloromethane;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 10 steps
1.1: Dess-Martin periodane / dichloromethane / 18 h / 20 °C / Cooling with ice
2.1: tetrahydrofuran / 2 h / 0 - 20 °C
3.1: hydrogen; palladium on activated charcoal / ethanol / 3 h
4.1: lithium borohydride / tetrahydrofuran / 3 h / -78 - 20 °C
5.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C
6.1: hydrazine hydrate / ethanol / 3 h / 70 °C
7.1: sodium hydrogencarbonate / ethanol; water / 20 °C
8.1: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C
8.2: 1 h / 110 °C
9.1: potassium hydroxide; methanol / tetrahydrofuran / 1 h / 20 °C
10.1: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 2 h / 20 °C
With
hydrogenchloride; methanol; lithium borohydride; di-isopropyl azodicarboxylate; palladium on activated charcoal; hydrogen; sodium hydrogencarbonate; Dess-Martin periodane; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; HATU; potassium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: tetrahydrofuran / 2 h / 0 - 20 °C
2.1: hydrogen; palladium on activated charcoal / ethanol / 3 h
3.1: lithium borohydride / tetrahydrofuran / 3 h / -78 - 20 °C
4.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C
5.1: hydrazine hydrate / ethanol / 3 h / 70 °C
6.1: sodium hydrogencarbonate / ethanol; water / 20 °C
7.1: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C
7.2: 1 h / 110 °C
8.1: potassium hydroxide; methanol / tetrahydrofuran / 1 h / 20 °C
9.1: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 2 h / 20 °C
With
hydrogenchloride; methanol; lithium borohydride; di-isopropyl azodicarboxylate; palladium on activated charcoal; hydrogen; sodium hydrogencarbonate; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; HATU; potassium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; water;