(S)-2-(4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)pyridin-2-yl)-N-(1,5-naphthyridin-4-yl)hydrazinecarboxamide

Base Information

Chemical Name:(S)-2-(4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)pyridin-2-yl)-N-(1,5-naphthyridin-4-yl)hydrazinecarboxamide
CAS No.:1456507-45-1
Molecular Formula:C₂₅H₂₃N₇O₃
Molecular Weight:469.503
Hs Code.:

Synonyms:(S)-2-(4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)pyridin-2-yl)-N-(1,5-naphthyridin-4-yl)hydrazinecarboxamide

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Chemical Property of (S)-2-(4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)pyridin-2-yl)-N-(1,5-naphthyridin-4-yl)hydrazinecarboxamide

Chemical Property:

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Technology Process of (S)-2-(4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)pyridin-2-yl)-N-(1,5-naphthyridin-4-yl)hydrazinecarboxamide

There total 4 articles about (S)-2-(4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)pyridin-2-yl)-N-(1,5-naphthyridin-4-yl)hydrazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 27392-68-3
4-amino-1,5-naphthyridine

: 32315-10-9
bis(trichloromethyl) carbonate

: 1456507-44-0
(S)-3-(2-hydrazinylpyridin-4-yl)-5,5-dimethyl-4-phenyloxazolidin-2-one

: 1456507-45-1
(S)-2-(4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)pyridin-2-yl)-N-(1,5-naphthyridin-4-yl)hydrazinecarboxamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;

Reference yield:

: 1456507-43-9
(S)-3-(2-chloropyridin-4-yl)-5,5-dimethyl-4-phenyloxazolidin-2-one

: 1456507-45-1
(S)-2-(4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)pyridin-2-yl)-N-(1,5-naphthyridin-4-yl)hydrazinecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine / 0.25 h / 140 °C

2: triethylamine / dichloromethane / 0 - 20 °C

With triethylamine; hydrazine; In dichloromethane;

Reference yield:

: 153034-86-7
2-chloro-4-iodopyridine

: 1456507-45-1
(S)-2-(4-(5,5-dimethyl-2-oxo-4-phenyloxazolidin-3-yl)pyridin-2-yl)-N-(1,5-naphthyridin-4-yl)hydrazinecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: potassium phosphate; N,N`-dimethylethylenediamine; copper(l) iodide / 1,4-dioxane / 0.67 h / 140 °C / Inert atmosphere; Microwave irradiation

2: hydrazine / 0.25 h / 140 °C

3: triethylamine / dichloromethane / 0 - 20 °C

With potassium phosphate; copper(l) iodide; triethylamine; hydrazine; N,N`-dimethylethylenediamine; In 1,4-dioxane; dichloromethane;