(S)-6-(2-Amino-4,5-dimethyl-phenylamino)-2-tert-butoxycarbonylamino-hexanoic acid

Base Information

Chemical Name:(S)-6-(2-Amino-4,5-dimethyl-phenylamino)-2-tert-butoxycarbonylamino-hexanoic acid
CAS No.:195812-21-6
Molecular Formula:C₁₉H₃₁N₃O₄
Molecular Weight:365.473
Hs Code.:

Synonyms:(S)-6-(2-Amino-4,5-dimethyl-phenylamino)-2-tert-butoxycarbonylamino-hexanoic acid

Suppliers and Price of (S)-6-(2-Amino-4,5-dimethyl-phenylamino)-2-tert-butoxycarbonylamino-hexanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (S)-6-(2-Amino-4,5-dimethyl-phenylamino)-2-tert-butoxycarbonylamino-hexanoic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (S)-6-(2-Amino-4,5-dimethyl-phenylamino)-2-tert-butoxycarbonylamino-hexanoic acid

There total 6 articles about (S)-6-(2-Amino-4,5-dimethyl-phenylamino)-2-tert-butoxycarbonylamino-hexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 195812-20-5
(S)-2-amino-N^α-(tert-butyloxycarbonyl)-6-(4',5'-dimethyl-2'-nitroanilin-N-yl)hexanoic acid

: 195812-21-6
(S)-6-(2-Amino-4,5-dimethyl-phenylamino)-2-tert-butoxycarbonylamino-hexanoic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; Yield given;
DOI:10.1002/anie.199714611

Reference yield:

: 6972-71-0
4,5-dimethyl-2-nitrobenzenamine

: 195812-21-6
(S)-6-(2-Amino-4,5-dimethyl-phenylamino)-2-tert-butoxycarbonylamino-hexanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 41 g / potassium persulfate, conc.H₂SO₄ / H₂O / Ambient temperature

2: 50 percent / HNO₃, H₂O₂ / acetic acid / 2 h / 100 °C

3: 74 percent / pyridine / 72 h / Heating

4: H₂ / Pd/C / acetic acid / 24 h

With potassium peroxomonosulphate; sulfuric acid; hydrogen; dihydrogen peroxide; nitric acid; palladium on activated charcoal; In pyridine; water; acetic acid;
DOI:10.1021/jo980643l

Reference yield:

: 13734-28-6
Boc-Lys-OH

: 195812-21-6
(S)-6-(2-Amino-4,5-dimethyl-phenylamino)-2-tert-butoxycarbonylamino-hexanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / pyridine / 72 h / Heating

2: H₂ / Pd/C / acetic acid / 24 h

With hydrogen; palladium on activated charcoal; In pyridine; acetic acid;
DOI:10.1021/jo980643l