4-methoxycarbonyl-4''-octyloxy-[1,1':4',1'']terphenyl

Base Information

• Chemical Name: 4-methoxycarbonyl-4''-octyloxy-[1,1':4',1'']terphenyl
• CAS No.: 1315480-30-8
• Molecular Formula: C₂₈H₃₂O₃
• Molecular Weight: 416.56
• Mol file: 1315480-30-8.mol

Synonyms:4-methoxycarbonyl-4''-octyloxy-[1,1':4',1'']terphenyl

Chemical Property of 4-methoxycarbonyl-4''-octyloxy-[1,1':4',1'']terphenyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methoxycarbonyl-4''-octyloxy-[1,1':4',1'']terphenyl

There total 1 articles about 4-methoxycarbonyl-4''-octyloxy-[1,1':4',1'']terphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-4'-hydroxybiphenyl (29558-77-8) → 4-methoxycarbonyl-4''-octyloxy-[1,1':4',1'']terphenyl (1315480-30-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / butanone / 8 h / Reflux

2.1: n-butyllithium / tert-butyl methyl ether / 2 h / -20 °C / Inert atmosphere

2.2: -60 - 20 °C / Inert atmosphere

2.3: 0.17 h / 20 °C

3.1: palladium diacetate; sodium carbonate; triphenylphosphine / water; isopropyl alcohol; toluene / 4 h / Inert atmosphere; Reflux

With n-butyllithium; palladium diacetate; sodium carbonate; potassium carbonate; triphenylphosphine; In tert-butyl methyl ether; water; isopropyl alcohol; toluene; butanone; 3.1: Suzuki coupling;

DOI:10.1016/j.tet.2012.02.015

Reference yield:

4-methoxycarbonyl-4''-octyloxy-[1,1':4',1'']terphenyl (1315480-30-8) → C42H56N4O7

Guidance literature:

Multi-step reaction with 4 steps

1.1: cetyltrimethylammonim bromide; potassium hydroxide / 5,5-dimethyl-1,3-cyclohexadiene; water / 3 h / Reflux

1.2: pH 1

2.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 48 h

3.1: N,N-dimethyl-formamide / 24 h / 20 °C

4.1: trifluoroacetic acid / dichloromethane / 0.75 h / 20 °C

With dmap; cetyltrimethylammonim bromide; dicyclohexyl-carbodiimide; trifluoroacetic acid; potassium hydroxide; In 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2012.02.015

Reference yield:

4-methoxycarbonyl-4''-octyloxy-[1,1':4',1'']terphenyl (1315480-30-8) → C43H58N4O6

Guidance literature:

Multi-step reaction with 4 steps

1.1: cetyltrimethylammonim bromide; potassium hydroxide / 5,5-dimethyl-1,3-cyclohexadiene; water / 3 h / Reflux

1.2: pH 1

2.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 48 h

3.1: N,N-dimethyl-formamide / 24 h / 20 °C

4.1: trifluoroacetic acid / dichloromethane / 0.75 h / 20 °C

With dmap; cetyltrimethylammonim bromide; dicyclohexyl-carbodiimide; trifluoroacetic acid; potassium hydroxide; In 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2012.02.015

upstream raw materials:

4-bromo-4'-hydroxybiphenyl

Downstream raw materials:

Nδ-Boc-Orn(Nα-4''-octyloxy-terphenyl-4-formyl)-Thr-Pro-OMe

Nδ-Boc-Orn(Nα-4''-octyloxy-terphenyl-4-formyl)-Val-Pro-OMe