C₆₁H₇₄N₂O₃

Base Information

• Chemical Name: C₆₁H₇₄N₂O₃
• CAS No.: 1419402-76-8
• Molecular Formula: C₆₁H₇₄N₂O₃
• Molecular Weight: 883.27
• Mol file: 1419402-76-8.mol

Synonyms:C₆₁H₇₄N₂O₃

Chemical Property of C₆₁H₇₄N₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₁H₇₄N₂O₃

There total 6 articles about C₆₁H₇₄N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C41H44INO3 (1419402-75-7) + N,N-dihexyl-4-[2-(trimethylsilyl)ethynyl]benzenamine (689250-82-6) → C61H74N2O3 (1419402-76-8)

Guidance literature:

With copper(l) iodide; bis(triphenylphosphine)palladium(II) dichloride; tetrabutyl ammonium fluoride; triethylamine; In toluene; at 40 ℃; for 15h; Inert atmosphere;

DOI:10.1002/chem.201202832

Reference yield:

C23H29NO3Si (1419402-73-5) → C61H74N2O3 (1419402-76-8)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride; triethylamine; bis(triphenylphosphine)palladium(II) dichloride; copper(l) iodide / toluene / 15 h / 40 °C / Inert atmosphere

2: tetrabutyl ammonium fluoride; triethylamine; bis(triphenylphosphine)palladium(II) dichloride; copper(l) iodide / toluene / 15 h / 40 °C / Inert atmosphere

With copper(l) iodide; bis(triphenylphosphine)palladium(II) dichloride; tetrabutyl ammonium fluoride; triethylamine; In toluene; 1: |Sonogashira Cross-Coupling / 2: |Sonogashira Cross-Coupling;

DOI:10.1002/chem.201202832

Reference yield:

hydroquinone (123-31-9,8027-02-9) → C61H74N2O3 (1419402-76-8)

Guidance literature:

Multi-step reaction with 5 steps

1: diethylazodicarboxylate; triphenylphosphine / tetrahydrofuran / 16 h / 20 °C / Inert atmosphere

2: dmap; triethylamine / dichloromethane / 14 h / 20 °C / Inert atmosphere

3: triethylamine; bis(triphenylphosphine)palladium(II) dichloride; copper(l) iodide / toluene / 15 h / 40 °C / Inert atmosphere

4: tetrabutyl ammonium fluoride; triethylamine; bis(triphenylphosphine)palladium(II) dichloride; copper(l) iodide / toluene / 15 h / 40 °C / Inert atmosphere

5: tetrabutyl ammonium fluoride; triethylamine; bis(triphenylphosphine)palladium(II) dichloride; copper(l) iodide / toluene / 15 h / 40 °C / Inert atmosphere

With dmap; copper(l) iodide; bis(triphenylphosphine)palladium(II) dichloride; tetrabutyl ammonium fluoride; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; toluene; 1: |Mitsunobu Displacement / 3: |Sonogashira Cross-Coupling / 4: |Sonogashira Cross-Coupling / 5: |Sonogashira Cross-Coupling;

DOI:10.1002/chem.201202832

upstream raw materials:

4-{2-[ethyl-(4-iodophenyl)amino]ethoxy}phenol

N,N-dihexyl-4-iodobenzenamine

C₄₁H₄₄INO₃

N,N-dihexyl-4-[2-(trimethylsilyl)ethynyl]benzenamine