Technology Process of 4,6,9-Trihydroxy-7-methyl-1H,3H-naphtho[1,8-cd]pyran-1,3-dione
There total 7 articles about 4,6,9-Trihydroxy-7-methyl-1H,3H-naphtho[1,8-cd]pyran-1,3-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid; scandium tris(trifluoromethanesulfonate);
In
ethyl acetate;
at 20 ℃;
for 6h;
DOI:10.1021/acs.orglett.0c03401
- Guidance literature:
-
Multi-step reaction with 6 steps
1: tetra-(n-butyl)ammonium iodide; potassium carbonate / N,N-dimethyl-formamide / 4.5 h / 20 °C
2: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 5.5 h / 40 °C
3: water; sodium hydroxide / ethanol; tetrahydrofuran / 20 °C
4: sulfuric acid / dichloromethane; methanol / 48 h / 40 °C
5: pyridine hydrochloride / 1.5 h / 165 °C
6: 3-chloro-benzenecarboperoxoic acid; scandium tris(trifluoromethanesulfonate) / ethyl acetate / 6 h / 20 °C
With
sulfuric acid; water; pyridine hydrochloride; tetra-(n-butyl)ammonium iodide; sodium hydrogencarbonate; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; scandium tris(trifluoromethanesulfonate);
In
tetrahydrofuran; methanol; ethanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
2: |Baeyer-Villiger Ketone Oxidation;
DOI:10.1021/acs.orglett.0c03401
