5-(4-chloro-2-(2-chlorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole

Base Information

Chemical Name:5-(4-chloro-2-(2-chlorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole
CAS No.:1580001-20-2
Molecular Formula:C₂₂H₁₇Cl₂N₃OS
Molecular Weight:442.368
Hs Code.:

Synonyms:5-(4-chloro-2-(2-chlorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole

Suppliers and Price of 5-(4-chloro-2-(2-chlorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-(4-chloro-2-(2-chlorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(4-chloro-2-(2-chlorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole

There total 10 articles about 5-(4-chloro-2-(2-chlorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

: 1580001-10-0
5-(4-chloro-2-(2-chlorophenoxy)benzyl)-2H-1,2,4-triazole-3(4H)-thione

: 1580001-20-2
5-(4-chloro-2-(2-chlorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole

Guidance literature:: With sodium hydroxide; In ethanol; water; for 0.0833333h; Sonication;
DOI:10.1016/j.bmc.2014.01.041

Reference yield:

: 69199-99-1
4-chloro-2-(2-chlorophenoxy)benzoic acid

: 1580001-20-2
5-(4-chloro-2-(2-chlorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole

Guidance literature:: Multi-step reaction with 8 steps

1.1: thionyl chloride / 4 h / Reflux

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 24 h / 20 °C / Cooling with ice; Inert atmosphere

3.1: thionyl chloride; pyridine / benzene / 4 h / Reflux; Inert atmosphere

4.1: dimethyl sulfoxide / 2 h / 20 °C

5.1: potassium hydroxide / butan-1-ol / 24 h / Reflux

6.1: thionyl chloride / 1 h / 50 - 55 °C

7.1: pyridine / benzene / -5 - 20 °C

7.2: 4 h / Reflux

8.1: sodium hydroxide / ethanol; water / 0.08 h / Sonication

With pyridine; lithium aluminium tetrahydride; thionyl chloride; potassium hydroxide; sodium hydroxide; In tetrahydrofuran; ethanol; water; dimethyl sulfoxide; butan-1-ol; benzene;
DOI:10.1016/j.bmc.2014.01.041

Reference yield:

: 38402-11-8
2,4-dichlorobenzoic acid sodium salt

: 1580001-20-2
5-(4-chloro-2-(2-chlorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole

Guidance literature:: Multi-step reaction with 9 steps

1.1: copper / water-d2 / Reflux

2.1: thionyl chloride / 4 h / Reflux

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 24 h / 20 °C / Cooling with ice; Inert atmosphere

4.1: thionyl chloride; pyridine / benzene / 4 h / Reflux; Inert atmosphere

5.1: dimethyl sulfoxide / 2 h / 20 °C

6.1: potassium hydroxide / butan-1-ol / 24 h / Reflux

7.1: thionyl chloride / 1 h / 50 - 55 °C

8.1: pyridine / benzene / -5 - 20 °C

8.2: 4 h / Reflux

9.1: sodium hydroxide / ethanol; water / 0.08 h / Sonication

With pyridine; lithium aluminium tetrahydride; thionyl chloride; copper; potassium hydroxide; sodium hydroxide; In tetrahydrofuran; ethanol; water; water-d2; dimethyl sulfoxide; butan-1-ol; benzene;
DOI:10.1016/j.bmc.2014.01.041