(R)-(-)-2-phenylglutaric acid

Base Information

Chemical Name:(R)-(-)-2-phenylglutaric acid
CAS No.:56581-84-1
Molecular Formula:C₁₁H₁₂O₄
Molecular Weight:208.214
Hs Code.:

Synonyms:(R)-(-)-2-phenylglutaric acid

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Chemical Property of (R)-(-)-2-phenylglutaric acid

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Technology Process of (R)-(-)-2-phenylglutaric acid

There total 7 articles about (R)-(-)-2-phenylglutaric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 346000-87-1
(2R)-5-oxo-5-(2-oxo(1,3-oxazolidin-3-yl))-2-phenylpentanoic acid

: 56581-84-1
(R)-(-)-2-phenylglutaric acid

Guidance literature:: With lithium hydroxide; dihydrogen peroxide; In tetrahydrofuran; water; for 1h;
DOI:10.1021/ja010302g

Reference yield:

: 1-(tert-butylthio)-5-(2-oxo(1,3-oxazolidin-3-yl))-2-phenylpentane-1,5-dione

: 56581-84-1
(R)-(-)-2-phenylglutaric acid

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / NBS; H₂O / tetrahydrofuran / 0.75 h / 20 °C

2: 97 percent / LiOH*H₂O; H₂O₂ / tetrahydrofuran; H₂O / 1 h

With lithium hydroxide; N-Bromosuccinimide; water; dihydrogen peroxide; In tetrahydrofuran; water;
DOI:10.1021/ja010302g