C₄₄H₅₈N₁₀O₁₃

Base Information

• Chemical Name: C₄₄H₅₈N₁₀O₁₃
• CAS No.: 1469300-28-4
• Molecular Formula: C₄₄H₅₈N₁₀O₁₃
• Molecular Weight: 935.004
• Mol file: 1469300-28-4.mol

Synonyms:C₄₄H₅₈N₁₀O₁₃

Chemical Property of C₄₄H₅₈N₁₀O₁₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₅₈N₁₀O₁₃

There total 11 articles about C₄₄H₅₈N₁₀O₁₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

C20H27N5O6 (1469300-38-6) + C24H33N5O8 (1469300-39-7) → C44H58N10O13 (1469300-28-4)

Guidance literature:

C₂₄H₃₃N₅O₈; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; for 0.166667h; Inert atmosphere;

C₂₀H₂₇N₅O₆; In dichloromethane; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1002/anie.201304239

Reference yield:

C13H17N3O3 → C44H58N10O13 (1469300-28-4)

Guidance literature:

Multi-step reaction with 7 steps

1.1: boron trifluoride diethyl etherate / acetonitrile / 0.17 h / 0 °C / Inert atmosphere

2.1: acetyl chloride / 4.5 h / 0 - 50 °C / Inert atmosphere

3.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 6 h / 760.05 Torr

4.1: lithium hydroxide monohydrate; water / d⁽⁴⁾-methanol; tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

5.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

5.2: 12 h / 20 °C / Inert atmosphere

6.1: trifluoroacetic acid / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

7.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

7.2: 12 h / 20 °C / Inert atmosphere

With lithium hydroxide monohydrate; palladium 10% on activated carbon; boron trifluoride diethyl etherate; water; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; acetyl chloride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; d⁽⁴⁾-methanol; ethyl acetate; acetonitrile;

DOI:10.1002/anie.201304239

Reference yield:

C13H14N4O2 (1469300-41-1) → C44H58N10O13 (1469300-28-4)

Guidance literature:

Multi-step reaction with 6 steps

1.1: acetyl chloride / 4.5 h / 0 - 50 °C / Inert atmosphere

2.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 6 h / 760.05 Torr

3.1: lithium hydroxide monohydrate; water / d⁽⁴⁾-methanol; tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

4.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

4.2: 12 h / 20 °C / Inert atmosphere

5.1: trifluoroacetic acid / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

6.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

6.2: 12 h / 20 °C / Inert atmosphere

With lithium hydroxide monohydrate; palladium 10% on activated carbon; water; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; acetyl chloride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; d⁽⁴⁾-methanol; ethyl acetate;

DOI:10.1002/anie.201304239

upstream raw materials:

C₁₄H₁₇N₃O₄

C₁₂H₂₁NO₆

C₁₂H₂₀N₄O₅

C₁₉H₂₇NO₆