1H-Indole, 5-bromo-3-(4-piperidinylmethyl)-

Base Information

Chemical Name:1H-Indole, 5-bromo-3-(4-piperidinylmethyl)-
CAS No.:75259-63-1
Molecular Formula:C₁₄H₁₇BrN₂
Molecular Weight:293.206
Hs Code.:
DSSTox Substance ID:DTXSID40226227
Wikidata:Q83105570
Pharos Ligand ID:P6TMUN32Q9BK
ChEMBL ID:CHEMBL25416

Synonyms:BRN 5544324;1H-Indole, 5-bromo-3-(4-piperidinylmethyl)-;CHEMBL25416;5-Bromo-3-(4-piperidinylmethyl)-1H-indole;75259-63-1;DTXSID40226227;BDBM50029148;LS-82416;5-Bromo-3-piperidin-4-ylmethyl-1H-indole

Suppliers and Price of 1H-Indole, 5-bromo-3-(4-piperidinylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1H-Indole, 5-bromo-3-(4-piperidinylmethyl)-

Chemical Property:

Vapor Pressure:2.97E-08mmHg at 25°C
Boiling Point:449°Cat760mmHg
Flash Point:225.3°C
Density:1.4g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:292.05751
Heavy Atom Count:17
Complexity:253

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1CC2=CNC3=C2C=C(C=C3)Br

Technology Process of 1H-Indole, 5-bromo-3-(4-piperidinylmethyl)-

There total 2 articles about 1H-Indole, 5-bromo-3-(4-piperidinylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 75259-76-6
(5-Bromo-1H-indol-3-yl)-piperidin-4-yl-methanone; hydrochloride

: 75259-63-1
5-Bromo-3-piperidin-4-ylmethyl-1H-indole

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; 1.) 20 deg C, 3 h, 2.) reflux, 15 min;
DOI:10.1021/jm00186a005

Reference yield:

: 4-(5-Bromo-1H-indole-3-carbonyl)-piperidine-1-carboxylic acid benzyl ester

: 75259-63-1
5-Bromo-3-piperidin-4-ylmethyl-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: 5 N HCl / ethanol / 4 h / Heating

2: 34 percent / LiAlH₄ / tetrahydrofuran / 1.) 20 deg C, 3 h, 2.) reflux, 15 min

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00186a005