3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine hydrochloride

Base Information

Chemical Name:3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine hydrochloride
CAS No.:1255305-41-9
Molecular Formula:C₂₀H₂₃NO₂*ClH
Molecular Weight:345.869
Hs Code.:

Synonyms:3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine hydrochloride

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Technology Process of 3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine hydrochloride

There total 1 articles about 3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 1255305-40-8
tert-butyl 3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine-1-carboxylate

: 1255305-41-9
3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine hydrochloride

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 0 - 20 ℃; for 0.666667h;

Reference yield: 62.0%

: 923169-37-3
4-(hydroxymethyl)pyridine-2-carboxylic acid

: 1255305-41-9
3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine hydrochloride

: 1255304-34-7
{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidin-1-yl}-4-hydroxymethylpyridin-2-yl-methanone

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 21h;

Reference yield: 62.0%

: 22468-26-4
4-hydroxypyridine-2-carboxylic acid

: 1255305-41-9
3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine hydrochloride

: 1255305-45-3
{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidin-1-yl}-4-hydroxypyridin-2-yl-methanone

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 21h;
DOI:10.1016/j.bmcl.2019.02.006