5-Iodo-2-methyl-3-nitroaniline

Base Information

Chemical Name:5-Iodo-2-methyl-3-nitroaniline
CAS No.:6942-35-4
Molecular Formula:C7H7IN2O2
Molecular Weight:278.0472
Hs Code.:
NSC Number:57461
DSSTox Substance ID:DTXSID10288756
Wikidata:Q82025847

Synonyms:5-iodo-2-methyl-3-nitroaniline;6942-35-4;NSC57461;NCIOpen2_007824;SCHEMBL4748778;DTXSID10288756;NSC-57461

Suppliers and Price of 5-Iodo-2-methyl-3-nitroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 5-Iodo-2-methyl-3-nitroaniline

Chemical Property:

Vapor Pressure:6.93E-06mmHg at 25°C
Boiling Point:377.1°C at 760 mmHg
Flash Point:181.8°C
Density:1.959g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:277.95523
Heavy Atom Count:12
Complexity:183

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(C=C1[N+](=O)[O-])I)N

Technology Process of 5-Iodo-2-methyl-3-nitroaniline

There total 2 articles about 5-Iodo-2-methyl-3-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6633-30-3
2,6-dinitro-4-iodo-toluene

: 6942-35-4
5-iodo-2-methyl-3-nitroaniline

Guidance literature:: With ammonium hydroxide; hydrogen sulfide; In 1,4-dioxane;
DOI:10.1039/j39700001480

Reference yield:

: 606-20-2
2,6-dinitrotoluene

: 6942-35-4
5-iodo-2-methyl-3-nitroaniline

Guidance literature:: Multi-step reaction with 2 steps

1: I₂, SO₃/H₂SO₄

2: H₂S, aq. NH₃ / dioxane

With ammonium hydroxide; sulfuric acid; hydrogen sulfide; sulfur trioxide; iodine; In 1,4-dioxane;
DOI:10.1039/j39700001480

Reference yield:

: 6942-35-4
5-iodo-2-methyl-3-nitroaniline

: 1058142-22-5
1-(4-amino-1-benzyl-1H-indazol-6-yl)pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: sodium nitrate; acetic acid / 4 - 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 2 - 3 h / 70 - 80 °C

3: copper; potassium carbonate / N,N-dimethyl-formamide / 10 - 12 h / 130 - 150 °C

4: hydrogen / nickel / methanol / 2 - 3 h / 3102.97 Torr

With sodium nitrate; hydrogen; copper; potassium carbonate; acetic acid; nickel; In methanol; N,N-dimethyl-formamide;