benzyl-1 (α-methoxy-4' phenyl)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine

Base Information

• Chemical Name: benzyl-1 (α-methoxy-4' phenyl)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine
• CAS No.: 102998-55-0
• Molecular Formula: C₂₃H₂₁ClN₂O
• Molecular Weight: 376.886
• Mol file: 102998-55-0.mol

Synonyms:benzyl-1 (α-methoxy-4' phenyl)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine

Chemical Property of benzyl-1 (α-methoxy-4' phenyl)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl-1 (α-methoxy-4' phenyl)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine

There total 5 articles about benzyl-1 (α-methoxy-4' phenyl)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1-benzyl-4-chloro-2-(1-(4-methoxyphenyl)vinyl)-1H-pyrrolo[3,2-c]pyridine (102998-48-1) → benzyl-1 (α-methoxy-4' phenyl)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine (102998-55-0)

Guidance literature:

With hydrogen; rhodium; aluminium; In ethanol; for 48h; Ambient temperature; at normal pressure;

DOI:10.1139/v86-087

Reference yield: 64.0%

1-Benzyl-2-[1-(4-methoxy-phenyl)-ethyl]-1,5-dihydro-pyrrolo[3,2-c]pyridin-4-one (102998-52-7) → benzyl-1 (α-methoxy-4' phenyl)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine (102998-55-0)

Guidance literature:

With trichlorophosphate; for 5h; Heating;

DOI:10.1139/v86-087

Reference yield:

benzyl-1 (α-methoxy-4' phenyl α-hydroxy)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine (102998-41-4) → benzyl-1 (α-methoxy-4' phenyl)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine (102998-55-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 68.2 percent / acetic anhydride / 20 h / Heating

2: 69 percent / H₂ / Rh on aluminum / ethanol / 48 h / Ambient temperature; at normal pressure

With hydrogen; rhodium; aluminium; In ethanol; acetic anhydride;

DOI:10.1139/v86-087

upstream raw materials:

1-benzyl-4-chloro-2-(1-(4-methoxyphenyl)vinyl)-1H-pyrrolo[3,2-c]pyridine

1-Benzyl-2-[1-(4-methoxy-phenyl)-ethyl]-1,5-dihydro-pyrrolo[3,2-c]pyridin-4-one

1-Benzyl-2-[1-(4-methoxy-phenyl)-vinyl]-1,5-dihydro-pyrrolo[3,2-c]pyridin-4-one

benzyl-1 (α-methoxy-4' phenyl α-hydroxy)ethyl-2 chloro-4 pyrrolo<3,2-c>pyridine

Downstream raw materials:

benzyl-1 (α-p-methoxyphenyl)ethyl-2 formyl-3 chloro-4 pyrrolo<3,2-c>pyridine