C₁₇H₁₆O₅

Base Information

• Chemical Name: C₁₇H₁₆O₅
• CAS No.: 1260148-62-6
• Molecular Formula: C₁₇H₁₆O₅
• Molecular Weight: 300.311
• Mol file: 1260148-62-6.mol

Synonyms:C₁₇H₁₆O₅

Chemical Property of C₁₇H₁₆O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₆O₅

There total 4 articles about C₁₇H₁₆O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 2-(3,5-bis(benzyloxy)-2-formylphenyl)acetate (1260148-61-5) → C17H16O5 (1260148-62-6)

Guidance literature:

methyl 2-(3,5-bis(benzyloxy)-2-formylphenyl)acetate; With boron tribromide; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

With hydrogenchloride; In dichloromethane; water; at 0 ℃;

DOI:10.1021/ol102652t

Reference yield:

methyl 2-(3,5-dihydroxyphenyl)acetate (4724-10-1) → C17H16O5 (1260148-62-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / acetone / Reflux; Inert atmosphere

2.1: trichlorophosphate / 16.17 h / 20 - 100 °C / Inert atmosphere

2.2: 0 °C

3.1: boron tribromide / dichloromethane / -78 - 20 °C / Inert atmosphere

3.2: 0 °C

With boron tribromide; potassium carbonate; trichlorophosphate; In dichloromethane; acetone;

DOI:10.1021/ol102652t

Reference yield:

2-(3,5-dihydroxyphenyl)acetic acid (4670-09-1) → C17H16O5 (1260148-62-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sulfuric acid / 20 °C / Reflux

2.1: potassium carbonate / acetone / Reflux; Inert atmosphere

3.1: trichlorophosphate / 16.17 h / 20 - 100 °C / Inert atmosphere

3.2: 0 °C

4.1: boron tribromide / dichloromethane / -78 - 20 °C / Inert atmosphere

4.2: 0 °C

With sulfuric acid; boron tribromide; potassium carbonate; trichlorophosphate; In dichloromethane; acetone;

DOI:10.1021/ol102652t

upstream raw materials:

methyl 2-(3,5-bis(benzyloxy)-2-formylphenyl)acetate

methyl 2-(3,5-dihydroxyphenyl)acetate

2-(3,5-dihydroxyphenyl)acetic acid

methyl 2-(3,5-bis(benzyloxy)-2-formylphenyl)acetate

Downstream raw materials:

2-propenyl (2S,3S,3'aS,4S,5'R)-4-[2-[(1,1-dimethylethyl)diphenylsilyloxy]ethyl]-3',3'a,4,5,5',6'-hexahydro-3-methyl-5'-pentyl-8'-(2-propenyloxy)-spiro[furan-2(3H),2'-[2H]pyrano[2,3,4-de][1]benzopyran]-9'-carboxylate

C₁₇H₁₅IO₅

C₁₆H₁₃IO₄

C₃₀H₄₁IO₆Si